重度子痫前期与孕晚期S／D升高对FGR形成的交互作用探讨  

Exploration of the interaction about severe preeclampsia and higher S / D in the formationof FGR

作　　者：许正先[1] 刘丹[1] 陈敏枝[1] 

机构地区：[1]佛山市妇幼保健院妇女保健科,528000

出　　处：《国际医药卫生导报》2011年第18期2277-2279,共3页International Medicine and Health Guidance News

摘　　要：目的探讨重度子痫前期与S／D升高对FGR形成的交互作用。方法选择2009年1月一2010年12月在本院分娩的被确诊为子痫前期，孕晚期行产科多普勒检查能够得到孕晚期S／D值，并排除其他妊娠期合并症和并发症的患者204例作为本次研究的研究对象；用Logistic回归的方法分析重度子痫前期和孕晚期S／D升高（具体指S／D大于3．0）对FGR形成的交互作用。结果重度子痫前期相对于轻度子痫前期是FGR形成的危险因素，OR为3．61，95％CI为1．90．6．98；S／D≥3．0相对于S／D〈3．0也是FGR形成的危险因素，OR为2．90，95％CI为1．49。5．65。而两者对FGR的形成的交互作用并无统计学意义，OR为1．44，95％CI为0．36。5．75。结论积极治疗重度子痫前期，加强产前检查及时发现脐动脉血流异常，对于降低FGR的形成风险和提高新生儿的健康水平具有重要的实际意义。Objective To explore if severe preeclampsia and higher S / D have interaction in the formation of FGR. Methods From January 2009 to December 2010, 204 pregnant women who delivered their baby in our hospital were selected as our observation group, they were all diagnosed as preeclampsia and accepted obstetric Doppler at their third trimester and we can get their S/D value from the Doppler, and they had no pregnant complications, then we used Logistic regression to analyze severe preeclampsia and higher third trimester S/D （specifically referring to S/D greater than 3.0） with interaction in forming FGR. Results Compared with mild preeclampsia, severe preeclampsia has a greater risk in the formation of FGR, OR=3.61, 95% CI （1.90-6.98）. Compared with S/D〈3.0, S/D I〉 3.0 is a/so a risk factor in forming FGR, OR = 2.90, 95% C[ of （1.49-5.65）. However, the interaction of the severe preeclampsia and higher S / D at third trimester is not statistically significant in forming FGR, OR=1.44, 95% CI of （0.36- 5.75）. Conclusion Active treatment for severe preeclampsia, strengthening prenatal care to detect abnor- mal umbilical artery blood flow have very important significance to reduce the formation of FGR for improv- ing neonates health level.

关 键 词：重度子痫前期 S/D FGR 交互作用 

分 类 号：R714.244[医药卫生—妇产科学]