睡眠呼吸暂停综合征患者经鼻持续正压通气治疗相关影响因素的分析  

Influential Factor of Pressure and Effect of Nasal Continuous Positive Airway Pressure on the Patients with Obstructive Sleep Apnea Syndrome

作　　者：胡燕怡[1] 黄华兴[1] 曹梅[1] 陈晓军[1] 

机构地区：[1]广州医学院第二附属医院,广东广州510260

出　　处：《临床医学工程》2011年第9期1382-1383,共2页Clinical Medicine & Engineering

摘　　要：目的探索睡眠呼吸暂停综合征患者nCPAP治疗压力和疗效的相关影响因素。方法先将OSAS患者根据AHI分度进行治疗前后分析,再将患者根据肥胖程度进行治疗前后分析。结果患者nCPAP治疗压力与AHI、BMI正相关,相关系数顺次分别为0.47、0.38。重度患者BMI、颈围、治疗压力高于中度患者(P<0.01)。治疗前轻度肥胖组AHI、压力高于非肥胖组(P<0.01),中度肥胖组AHI、压力高于轻度肥胖组(P<0.01),中度肥胖组minSaO2低于轻度肥胖组(P<0.01),轻度肥胖组minSaO2低于非肥胖组(P<0.01)。治疗后各组压力无明显改变(P>0.05)。治疗后非肥胖组minSaO2高于轻度肥胖组及中度肥胖组(P<0.01)。各组治疗前后压力差异无统计学意义。结论患者不仅AHI,而且BMI、颈围也对nCPAP治疗压力和疗效存在影响。故在nCPAP呼吸机压力滴定和评估疗效时,要综合考虑以上多种因素的影响,并在拟定其他辅助治疗方案时减肥应放在首要位置。Objective To explore the influential factor of therapy pressure and effect of nasal-continuous positive airway pressure（nCPAP） treatment on the patients with obstructive sleep apnea syndrome（OSAS）.Methods OSAS patients were divided into different groups and analyzed before and after treatment according to AHI.Then they were divided into different groups and analyzed according to BMI.Results The therapy pressure had positive correlation with AHI and BMI,with coefficient 0.47,0.38 respectively.BMI,neck collar and pressure of severe OSAS group were higher than moderate group（P 0.01）.Before treatment AHI and pressure of moderate obesity group were higher than those of mild obesity group（P 0.01）,AHI and pressure of mild obesity group were higher than those of non-obesity group（P 0.01）,but minSaO2 of moderate obesity group was lower than that of mild obesity group（P 0.01）,minSaO2 of mild obesity group was lower than that of non-obesity group（P 0.01）.Pressure had no obvious difference after treatment（P 0.05）.After treatment minSaO2 of non-obesity group was higher than that of mild obesity and moderate obesity group（P 0.01）.Conclusion Not only AHI,but also BMI and neck collar will influence nCPAP therapy pressure and effect.So when chosing nCPAP treatment and evaluating the effect,all the factor concerned shall be considered.And when subordinate therapy is planned,weight reduction is the most important measure.

关 键 词：经鼻持续气道正压通气 压力 疗效 影响因素 

分 类 号：R766[医药卫生—耳鼻咽喉科]