酮咯酸氨丁三醇联合吗啡用于老年人术后自控镇痛的临床研究  

Clinical research of Ketorolac Tromethamine united Morphine for postoperative controlled analgesia in the elderly

作　　者：刘健[1] 蔡进[1] 林宇[1] 

机构地区：[1]武警福建总队医院麻醉科,福建福州350003

出　　处：《实用临床医药杂志》2011年第15期56-58,共3页Journal of Clinical Medicine in Practice

摘　　要：目的观察酮咯酸氨丁三醇联合吗啡用于老年人术后自控镇痛的疗效及不良反应。方法选择前列腺激光手术男性老年患者72例,随机分为A、B 2组,A组术后静脉维持使用酮咯酸氨丁三醇;B组术后静脉维持使用芬太尼。结果 2组病人镇痛效果(VAS评分)、镇静程度(Ramesay评分)、脉搏氧饱和度、心率和血压组间比较无差异。结论低剂量静脉酮咯酸氨丁三醇和硬膜外吗啡联合镇痛用于老年人可以显著降低阿片类药物不良反应发生率,对合并基础疾病的老年人而言该术后镇痛方式疗效确切且具有很高的安全性。Objective To observe the efficacy and adverse effects of Ketorolac Tromethamine united Morphine for postoperative analgesia in the elderly.Methods Seventy two elderly male patients who had prostate laser surgery were randomly divided into groups A,B.Group A received Ketorolac Tromethamine by continuous intravenous infusion postoperatively.Group B was given Fentanyl to maintain.Results Analgesic effect of patients （VAS score）,sedation（Ramesay score）,pulse oxygen saturation,heart rate and blood pressure showed no difference between the two groups.Conclusion Low-dose of intravenous Ketorolac Tromethamine and epidural Morphine analgesia for the elderly can significantly reduce opioid adverse reaction rates.For the combined diseases of the elderly,the postoperative analgesia is effective and highly safe.

关 键 词：患者静脉自控镇痛 酮咯酸氨丁三醇 老年 

分 类 号：R614.4[医药卫生—麻醉学]