医院感染鲍氏不动杆菌的临床分布及耐药性分析  

Clinical distribution and antimicrobial resistance of Acinetobacter baumannii causing nosocomial infections

作　　者：李智山[1] 肖慈然[2] 

机构地区：[1]襄阳市中心医院医学检验部,湖北襄阳441021 [2]贵阳医学院医学检验系,贵州贵阳550001

出　　处：《中华医院感染学杂志》2011年第18期3945-3946,共2页Chinese Journal of Nosocomiology

摘　　要：目的了解医院感染鲍氏不动杆菌(ABA)的临床分布及对抗菌药物的耐药性,为临床医师抗感染治疗提供科学依据。方法 223株ABA分离自医院患者感染性标本,采用法国生物梅里埃公司API 20NE试剂条进行细菌鉴定;采用K-B法进行药敏试验,依据CLSI最新折点判读结果。结果 ABA主要分离自呼吸道标本,占70.9%;对常用抗菌药物均产生了严重的耐药性,对亚胺培南和美罗培南耐药率分别为23.8%、24.7%,ABA泛耐药菌株检出率为17.5%。结论 ABA主要分离自呼吸道,对抗菌药物耐药现象严重,各级医院应重视细菌耐药性监控工作,预防多药耐药ABA医院感染的暴发流行。OBJECTIVE To understand the clinical distribution and antimicrobial resistance of Acinetobacter baumannii（ABA） causing nosocomial infections and provide the scientific evidence for clinical anti-infective treatment.METHODS A total of 223 ABA were isolated from infective specimen.API20NE（bioMérieux） was used to identify the strains.Drug susceptibility testing was performed by K-B methods.The test results were assessed according to the latest CLSI breakpoints.RESULTS The isolating rate of aba from respiratory tract（70.9%） was the highest.The serious resistance of commonly used antibiotics occurred in SBA,the resistance rates of imipenem and meropenem were 23.8% and 24.7%,respectively.The isolating rate of pan-resistant stains was 17.5%.CONCLUSION Hospitals should attach importance to monitoring of antimicrobial resistance to prevent the outbreak and epidemic of nosocomial infections caused by multidrug resistant ABA.

关 键 词：多药耐药 鲍氏不动杆菌 医院感染 耐药性 监测 

分 类 号：R378[医药卫生—病原生物学]