生物毒素战剂：检测识别分子与防治药物  

Toxin warfare agents:recognition molecules and drugs for control

作　　者：王景林[1] 

机构地区：[1]军事医学科学院微生物流行病研究所,病原微生物生物安全国家重点实验室,北京100071

出　　处：《军事医学》2011年第8期561-565,共5页Military Medical Sciences

基　　金：军队“十一五”计划专题项目(06Z069)

摘　　要：自然界中存在着种类繁多的毒素物质,但最有可能用作战剂的是那些获取方便、制备容易、毒性强、施放后可致人死亡或失能的毒素。毒素战剂既不同于传统的细菌、病毒战剂,也不同于化学毒剂,其最大的威胁来自它的高毒性及缺乏有效的治疗手段。因此,发展毒素战剂的检测识别分子与防治药物就显得尤为重要。本文讨论了生物毒素战剂相关概念、特征,重点综述了毒素战剂的检测识别分子与防治药物研究进展。There are various types of toxins in nature. However, these toxins, which are characterized by the ready availability, easy production and high toxicity, arc likely bi~）logical warfare agents. Toxin warfare agents are different from traditional bacterial and viral agents or from chemical warfare agents in that they pose a great threat because of their diverse potency and the lack of efficacious drugs. Therefore, it is quite important to develop specific, sensitive recognition mole- cules for detection of toxins and drugs against intoxication caused by toxin agents. This review focuses on advances in recog- nition molecules of toxins and some drugs used as prevention and treatment based on the characteristics of toxin warfare agents

关 键 词：生物毒素 生物战剂 识别分子 治疗药物 疫苗 

分 类 号：R827.2[医药卫生—临床医学]