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作 者:吴凯[1,2] 高音[2] 陈晓平[1] 李龙兴[1] 万里艳[1] 陈小妮
机构地区:[1]四川大学华西医院心内科,成都610041 [2]903医院心内科
出 处:《现代预防医学》2011年第18期3677-3680,共4页Modern Preventive Medicine
基 金:"十一五"科技支撑项目:代谢综合征的发病趋势和综合控制研究(2006BAI01A01)
摘 要:[目的]调查分析成都地区中老年居民脉压(PP)、脉压指数(PPI)的影响因素,寻找可能改善脉压异常的方法。[方法]利用2007代谢综合征研究调查资料(共1061人),把人群依据PP(PP≤60mmHg及PP﹥60mmHg)及PPI(PPI≤0.450及PPI﹥0.450)分为正常组及增高组,分析两组人群多代谢异常及心血管疾病危险因素分布特征,并采用Logistic回归分析寻找与PP/PPI相关的危险因素。[结果]①两个分组间年龄、收缩压、男性比重、高血压家族史、体重指数、腰围、臀围、空腹血糖、肾功能等指标PP、PPI增高组明显高于PP、PPI正常组,舒张压则是PP、PPI增高组明显低于PP、PPI正常组。②血脂各成分PP组间无统计学差异,总胆固醇、低密度脂蛋白水平PPI增高组高于正常组。③PP及PPI增高组其代谢综合征、高血压、糖尿病、肥胖、腹型肥胖、血脂异常等患病率皆高于PPI正常组,差异有统计学意义。④Logistic回归分析提示PP、PPI与女性性别、年龄、收缩压、BMI、腰围、臀围、空腹血糖、肌酐、尿酸、总胆固醇、低密度脂蛋白水平呈正相关,与男性性别及舒张压呈负相关。[结论]成都地区脉压及脉压指数与代谢性指标关系密切,可能可以通过改善血脂、空腹血糖、腰围、体重指数、肾功能等指标来减少脉压及脉压指数的异常。[Objective]To evaluate the influencing factors on pulse pressure(PP)and pulse presure index(PPI)among middle-aged residents in Chengdu,and search the possible methods to relieve PP disorder.[Methods]We divided the 1061 middle-aged people who came from the survey for metabolic syndrome study into 2 groups according to PP(PP≤60mmHg and PP﹥60mmHg)and PPI(PPI(PPI≤0.450 and PPI﹥0.450)).They were normal PP/PPI group and augmented PP/PPI group.The normal PP group mean the PP of the people was less than or equal to 60 mmHg,and normal PPI group was PPI less or equal to 0.450.The augmented PP/PPI group was PP more than 60 mmHg and PPI more than 0.450.We analyzed the distribution of risk factors relate to PP/PPI.[Results]① The indices of age,the proportion of men,systolic blood pressure(SBP),the rate of positive history of hypertension,Body mass index(BMI),waist circumference(WC),hip circumference(HC),fasting blood glucose(FBG),creatinine(CA)and uric acid(UA)in augmented PP/PPI group were higher than normal group,and there was significant difference between the two groups.As to diastolic blood pressure(DBP),the normal PP/PPI group was statistically higher than the augmented PP/PPI group.② There was no statistically difference on total cholesterol(TC),triglyceride(TG),high-density lipoprotein(HDL)and low-density lipoprotein(LDL)between the PP groups,and no difference between PPI groups on TG and HDL.But the TC and LDL in augmented PPI group were statistically higher than that in normal PPI group.③ The prevalence of metabolic syndrome,hypertension,diabetes mellitus,obesity,abdominal obesity and Dyslipidemia in augmented PP/PPI groups were all statistically higher than the normal groups.④ PP and PPI were positively related to female,age,SBP,BMI,WC,HC,FBG,creatinine,uric acid,TC and LDL by using Logistic regression analysis,and they were negatively related to male and DBP.[Conclusion]The PP and PPI were closely related to the metabolic indices i
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