左氧氟沙星治疗医院获得性肺炎疗效观察  

The clinical effect of levofloxacin used on patients with hospital acquired pneumonia（HAP）

作　　者：欧阳国栋[1] 蔡冰 吴渊[1] 廖雁 

机构地区：[1]佛山市顺德区慢性病防治中心结防利,广东省佛山528300 [2]皮肤科 [3]医务办

出　　处：《中国基层医药》2011年第19期2643-2644,共2页Chinese Journal of Primary Medicine and Pharmacy

摘　　要：目的探讨左氧氟沙星治疗医院获得性肺炎的临床效果。方法134例医院获得性肺炎患者在知情同意下按入院顺序随机分为观察组和对照组各67例，对照组给予阿奇霉素治疗，观察组给予左氧氟沙星治疗，观察比较两组显效率和总有效率。结果经过治疗，观察组显效51例、有效13例、无效3例、显效率75．0％、总有效率93．3％，对照组分别为38例、17例、12例、51．7％、81．7％，观察组显效率和总有效率均明显高于对照组（X2=4．818、4．804，均P〈0．05）。两组均未发生严重不良反应。结论左氧氟沙星治疗医院获得性肺炎可获得较好的临床治疗效果，不良反应轻。Objective To explore the clinical effect of levofloxacin used on patients with HAP. Methods 134 cases of patients with HAP as studied object were randomly divided into observation group and control group,observation group were given therapy of levofloxacin, and control group were given therapy of azithromycin. Results The efficien- cy cases, effective cases, vain eases in observation group were 51,13 and 3, the efficiency rate and total effective rate were 75.0% and 93.3%, the data in control group were 38,17,12,51.7% and 81.7%. The efficiency rate （ X2 4. 818, P 〈 0.05 ） and total effective rate （ X~ = 4.804, P 〈 0.05 ） of observation group was significantly better than that .of control group. Conclusion Levofloxaein used on patients with HAP, could acquire good clinical effect, and the side-reactions were light.

关 键 词：交叉感染 肺炎 左氧氟沙星 阿奇霉素 

分 类 号：R563[医药卫生—呼吸系统]