上海市浦东新区泌尿系结石患者与健康体检者结石相关因素的对照研究  

Analysis of Relative Factors of Urinary Stones Between Patients of Urinary Stone and the Health People in Shanghai Pudong Area

作　　者：顾燕[1] 王国增[1] 贺伟[1] 章璟[1] 杨佳伟[1] 杨芳[1] 叶敏[2] 

机构地区：[1]上海市浦东新区公利医院泌尿外科,上海200135 [2]上海交通大学附属新华医院泌尿外科

出　　处：《临床泌尿外科杂志》2011年第9期702-705,共4页Journal of Clinical Urology

基　　金：上海市卫生局科研课题资助(编号2008109)

摘　　要：目的:探讨泌尿系结石患者与健康体检者结石相关因素。方法:对300例泌尿系结石患者的结石成分进行分析,并结合血生化及24 h尿液分析结果,与300例健康体检者进行对照研究。结果:尿石症患者中,草酸钙结石232例(77.3%),磷酸盐结石50例(16.7%),感染性结石9例(3%),尿酸结石9例(3%)。结石患者血清镁、钙、磷及24 h尿氯、钙、镁、磷、尿酸显著高于健康体检者(P<0.05),而血钾、尿枸橼酸则显著低于健康体检者(P<0.05)。结论:尿结石与多种代谢异常关系密切,结石成分及代谢评估对泌尿系结石的成因、治疗和预防有重要临床指导意义。Objective：To study the relative factors of urinary stones between patients of urinary stone and the health people. Methods：The composition of the stone, entire blood biochemistry and 24 h urine of the 300 patients were evaluated, and then compared with the result of the health people. Results：Calcium oxalate stones were found in 232 cases（77.30/00）, phosphate stones in 50 cases（16.7%） ,infection stones in 9 cases（aN）, uric stones in 9 cases （3 %）. The urinary stone patients significantly greater blood magnesium, calcium, phosphorus and urine chlorine, calcium, magnesium, phosphorus,uric acid than the healthy people（P〈0.05）3 and significantly less blood Potassium, and urine citrate than the healthy people（P〈0.05）. Conclusions：Urinary stone recurrence is closely related with more than one kinds of metabolic disturbances. Stone composition analysis and metabolic evaluation are very important in finding the causes and in treating and preventing urinary stones.

关 键 词：尿路结石 结石分析 尿液分析 代谢评估 

分 类 号：R691.4[医药卫生—泌尿科学]