小鼠胚胎肾细胞凋亡与胀亡的超微结构  

Ultrastructure of apoptosis and oncosis in embryonic mouse kidney

作　　者：李潮[1] 邵姝元[2] 刘玉玲[3] 郭敏[4] 

机构地区：[1]辽宁医学院附属一院,锦州121001 [2]辽宁医学院病理生理学教研室,锦州121001 [3]辽宁医学院中心实验室,锦州121001 [4]辽宁医学院组织学与胚胎学教研室,锦州121001

出　　处：《解剖学杂志》2011年第4期484-486,共3页Chinese Journal of Anatomy

基　　金：辽宁省教育厅课题（L2010274）

摘　　要：目的：观察小鼠胚胎肾发育中细胞凋亡与胀亡的超微结构。方法：应用透射电子显微镜对不同胚龄大鼠肾进行了系统观察。结果：作为细胞程序性死亡的胀亡出现在发育的。肾中，但与凋亡相比出现的频率不高。凋亡与胀亡的不同仅在于细胞质的表现。结论：在肾发育中细胞凋亡仍然为主要的程序性细胞死亡，胀亡只处于辅助地位。Objective： To observe the uhrastructures of apoptosis and oncosis in embryonic mouse kidneys. Methods： Trans mission electron microscope was used in this study. Results： Oncosis could be found as a programmed cell death in embryonic mouse kidneys. However it was less obvious than apoptosis. Cytoplasm swelling of oncosis was the principal difference from apoptosis which had condensed cytoplasm. Conclusion： Apoptosis is more principle as programmed cell death than oncosis during kidney development.

关 键 词：凋亡 胀亡 肾发育 电镜 小鼠 

分 类 号：R692.5[医药卫生—泌尿科学]