山栀茶中一个新的三萜类化合物  

A new triterpenoid fom Radix Pittospori

作　　者：肖炳坤[1] 王伟兰[2] 黄荣清[1] 杨建云[1] 董俊兴[1] 

机构地区：[1]军事医学科学院放射与辐射医学研究所,北京100850 [2]解放军总医院药品保障中心,北京100853

出　　处：《药学学报》2011年第9期1101-1103,共3页Acta Pharmaceutica Sinica

基　　金：国家自然科学基金资助项目(81072613)

摘　　要：为了研究山栀茶(Radix Pittospori)的化学成分,运用多种色谱方法进行分离纯化,从其氯仿提取物中分离得到2个三萜类化合物,并根据理化性质和波谱数据鉴定其结构分别为22-acetyl-21-(2-acetoxy-2-methylbutanoyl)-R1-barrigenol(1)和3α-hydroxyl-20-demethylisoaleuritolic-14(15)-ene-28,30-dioic acid(2)。其中,化合物1为新的三萜类化合物,化合物2为首次从该植物中分离得到。To investigate chemical constituents from Radix Pittospori,chloroform extract of the roots was subjected to column chromatography with various chromatographic techniques.The structures were elucidated on the basis of physico-chemical property and spectral analysis.Two triterpenoids were identified as 22-acetyl-21-（2-acetoxy-2-methylbutanoyl）-R 1-barrigenol （1） and 3α-hydroxyl-20-demethylisoaleuritolic-14 （15）-ene-28,30-dioic acid（2）.Compound 1 is a new triterpene and compound 2 is isolated from this plant for the first time.

关 键 词：山栀茶 三萜 22-acetyl-21-(2-acetoxy-2-methylbutanoyl)-R1-barrigenol 

分 类 号：R284[医药卫生—中药学]