良乡地区成人住院社区获得性肺炎的病原体分布及其耐药性分析  

Analysis the Distribution and Drug Resistance of Pathogens from Adult Hospital Community Acquired Pneumonia Patients of Liangxiang Area

作　　者：乜庆荣[1] 刘新民[2] 安晓洁[1] 

机构地区：[1]北京市房山区良乡医院呼吸科,北京102401 [2]北京大学第一附属医院呼吸科,北京100013

出　　处：《中国临床医学》2011年第4期499-501,共3页Chinese Journal of Clinical Medicine

摘　　要：目的:调查良乡地区成人住院社区获得性肺炎(CAP)的病原菌分布状况,了解细菌的耐药情况,为CAP的经验性治疗提供依据。方法:2008年7月—2010年7月在良乡院住院的CAP患者共182例,分别留取呼吸道分泌物进行细菌学培养和血非典型病原体的检测。结果:在182例CAP患者80例(44.0%)痰细菌学检查阳性,主要病原菌为肺炎链球菌25例(13.7%)、流感嗜血杆菌15例(8.2%)。在行血清学检测的CAP患者中非典型病原体感染29例(15.9%)。肺炎链球菌对青霉素耐药率为44.0%,;流感嗜血杆菌对氨苄青霉素的耐药率为40.0%。结论:肺炎链球菌、流感嗜血杆菌和肺炎支原体是良乡地区成人CAP住院患者的主要致病菌,肺炎链球菌、流感嗜血杆菌对青霉素及大环内酯类耐药率较高。Objective：To investigate the distribution and drug resistance of pathogens of adult hospital community-acquired pneumonia（CAP） of LiangXiang area,so as to provide evidence for CAP empirical treatment.Methods： A total of 182 CAP patients treated in our hospital from July 2008 to July 2010 were Abstracted respiratory secretions to have the bacterial culture and the detect of atypical pathogens.Results： The culture of bacterial of 80 cases from 180 CAP patients（44.0%） were positive.The main isolated pathogens were Streptococcus pneumonias 25 cases（13.7%）,Hemophilia 15 cases（8.2%）.There were 29 cases atypical pathogens（15.9%） were found in CAP patients who had Serological test.Among them,the drug resistance rate of Streptococcus pneumonias to Penicillin was 44.0 percents.The drug resistance rate of Hemophilic to Ampicillin was 40 percents.Conclusions： The main pathogens of Adult hospital CAP are Streptococcus pneumonias、Hemophilic and Mycoplasma.The drug resistance rate of Streptococcus pneumonias and Hemophilic to Penicillin and Macrolides are high.The infection rate of atypical pathogens is high.

关 键 词：社区获得性肺炎 病原体 耐药性 

分 类 号：R563.1[医药卫生—呼吸系统]