酸碱度对三氯羟基二苯醚复方消毒剂杀灭微生物效果的影响研究  

STUDY ON INFLUENCE OF pH TO GERMICIDAL EFFICACY OF A COMPOUND DISINFECTANT OF TRICLOSAN AND ALCOHOL

作　　者：蒋莉[1] 任哲[1] 武雪冰[1] 饶林[1] 

机构地区：[1]军事医学科学院疾病预防控制所,北京100071

出　　处：《中国消毒学杂志》2011年第5期531-533,共3页Chinese Journal of Disinfection

摘　　要：目的观察酸碱度对三氯羟基二苯醚复方消毒剂杀灭微生物效果的影响。方法应用悬液定量杀菌试验方法,观察pH值对三氯羟基二苯醚复方消毒剂杀灭脊髓灰质炎病毒和大肠杆菌效果的影响。结果三种消毒剂A、B、C中三氯羟基二苯醚和乙醇含量相同,pH值分别为3.23,4.32和5.10。A、B、C等三种消毒剂均作用1 min,对悬液内脊髓灰质炎病毒的灭活对数值依次分别为>4.0、1.92和1.75。A和B消毒剂的5倍稀释液作用1 min,对悬液内大肠杆菌平均杀灭对数值分别为7.12和2.04;消毒剂C原液作用1 min,对大肠杆菌平均杀灭对数值为2.00。结论 pH值对三氯羟基二苯醚复方消毒剂杀灭微生物的效果有明显影响,pH值增加,杀菌效果下降。Objective To observe the influence of pH to germicidal efficacy of a compound disinfectant of triclosan and alcohol. Methods Quantitative germicidal test was used to observe the influence of pH to germicidal efficacy of the disin- fectant to poliovirus and Escherichia coli. Results The concentration of triclosan and alcohol of the disinfectant A, B and C are the same. The pH Value of the three disinfectants was 3.23, 4.32 and 5.10 respectively. The killing logarithm value of poliovirus in suspension by disinfectant A, B and C for 1 min was above 4.00, 1.92 and 1.75 respectively. The killing logarithm value of E coli by five folds dilution of disinfectant A and B for 1 min was 7.12 and 2.04 respectively. The killing logarithm value of E coli by disinfectant C for 1 min was 2.00. Conclusion pH has significant influence to the germicidal efficacy of the compound disinfectant of triclosan and alcohol. The germicidal efficacy decreases when the pH value of the disinfectant increases.

关 键 词：三氯羟基二苯醚 PH值 杀菌效果 影响因素 

分 类 号：R187.1[医药卫生—流行病学]