泛耐药鲍曼不动杆菌的临床分布及耐药性监测  

SURVAILLANCE ON ANTIBIOTICS RESISTANCE AND CLINICAL DISTRIBUTION OF PDR-AB

作　　者：宋志香[1] 薛文英[1] 胡凤军[1] 李岳[1] 

机构地区：[1]北京世纪坛医院,北京100038

出　　处：《中国消毒学杂志》2011年第5期576-578,共3页Chinese Journal of Disinfection

摘　　要：目的了解泛耐药鲍曼不动杆菌感染的分布特点及耐药性。方法采用回顾性调查方法,对北京某三级甲等医院2009年3月至11月住院病人临床送检标本检出的302株泛耐药鲍曼不动杆菌分布与抗菌药物耐药状况进行了调查与分析。结果在调查期间该医院从医院感染病人标本中检出的6种耐药菌分别是耐甲氧西林金黄色葡萄球菌、泛耐药鲍曼不动杆菌、ESBL+肺炎克雷伯、ESBL+大肠爱希菌、耐万古霉素肠球菌和铜绿假单胞菌,共计867株,其中泛耐药鲍曼不动杆菌构成比为34.83%。该菌株有89.16%来自痰标本,其次是尿液,占4.20%;其主要来自ICU病人标本和呼吸病房病人标本。该菌株对临床常用抗菌药物高度耐药和多重耐药,对亚胺培南耐药率高达94.98%。结论泛耐药鲍曼不动杆菌感染主要分布于呼吸道和泌尿道感染病人,呈现出多重耐药趋势。Objective To know the clinical distribution and antibiotics resistance of PDR - AB （ Pan - drug resistant acinetobacter baumannii） . Methods Retrospective investigation was used to analyze antibiotics resistance and clinical distribution of 302 strains of PDR - AB isolated from clinic specimens from March to November 2009 at a first hospital of three level in Beijing. Results There were 6 kinds of antibiotic - resistant bacteria of the specimens, which were MRSA, PDR - AB, KPN E ＋ , ECO E ＋ , VRE and PAE. The total were 867 strains. The ratio of PDR - AB was 34.83%. Of which, 89.16% was detected out in the sputum samples, 4.20% in urine samples. Most of PDR--AB were from ICU and the respiratory ward. PDR - AB show high - drug resistance and muhi - drug resistance, resistance rate to imipenem is 94.98%. Conclusion PDR - AB mostly make respiratory tract infection and urinary tract infection, show multiple drug - resistant trend.

关 键 词：泛耐药鲍曼不动杆菌 医院感染 临床分布 耐药性 防控措施 

分 类 号：R378[医药卫生—病原生物学]