益气活血中药治疗放射性肺损伤临床疗效观察  

The clinical effects of traditional Chinese medicine which supplements Qi and activates blood circulation on the X-ray radiotherapy-induced lung injury

作　　者：张晓敏[1] 王炳胜[2] 葛艳丽[2] 张建宇[2] 

机构地区：[1]河北省石家庄市第三医院药剂科,050011 [2]解放军第二五一医院肿瘤诊疗中心

出　　处：《中国综合临床》2011年第9期908-910,共3页Clinical Medicine of China

基　　金：全军“十一五”课题基金资助项目（06MB084）

摘　　要：目的观察益气活血中药治疗放射性肺损伤的临床疗效。方法在我院接受三维适形放疗的84例患者，随机分为治疗组44例和对照组40例。治疗组患者给予益气活血中药干预；对照组患者给予抗生素及激素等相应药物治疗。结果2个月后治疗组治疗效果明显优于对照组，总有效率分别为88．6％（39／44）和60．0％（24／40），差异有统计学意义（X2=9．16，P〈0．05）。治疗6个月后治疗组胸部cT特征与对照组比较，差异有统计学意义（x2=12．22，P〈0．05）。结论益气活血中药对放射性肺损伤有良好的治疗作用，对放射性肺纤维化有较好的预防作用。Objective To observe the effects of traditional Chinese medicine which supplements Qi and activates blood circulation on the treatment of the X-ray radiotherapy-induced lung injury. Methods Eighty-four patients who were given three-dimensional conformal radiotherapy were randomized into treatment group and control group. The patients in treatment group were given traditional Chinese medicine, which supplements Qi and activates blood circulation, while the patients in control group were given antibiotics and hormone instead. Results The outcome of treatment group was better than that of control. The response rates were gg. 6% and 60. （1%, respectively （ X2 = 9.16, P 〈 0. （15）. Compared with the patients in control group, the clinical manifestations and pulmonary CT reflected better response in the patients of the treatment group （x2 = 12. 22 ,P 〈 0. 05 ）. Conclusion The traditional Chinese medicine, which supplements Qi and activates blood circulation,has a good therapeutical effect on radiation pneumonitis and protective role for radiation-induced pulmonary fibrosis.

关 键 词：益气活血中药 三维适形放疗 放射性肺损伤 

分 类 号：R818[医药卫生—放射医学] R730.5[医药卫生—临床医学]