糖化白蛋白检测对妊娠期糖尿病患者的临床探讨  

Glycated albumin testing on clinical investigation of patients with gestational diabetes.

作　　者：王茜[1] 严斌[2] 韩思阳[1] 李阳[1] 王雪冬[1] 

机构地区：[1]齐齐哈尔医学院第五附属大庆龙南医院,163453 [2]上海交通大学附属仁济医院

出　　处：《中国优生与遗传杂志》2011年第9期72-72,98,共2页Chinese Journal of Birth Health & Heredity

摘　　要：目的探讨糖化白蛋白(GA)的测定对妊娠期糖尿病患者筛查诊断治疗价值,为临床应用GA提供参考。方法选取2009年l月～2010年8月在我院产前检查的正常孕妇(对照组A组)40例、妊娠期糖代谢异常孕妇(B组)40例中空腹血糖(FPG)、糖化血红蛋白(HbA1c)和GA,并对B组患者治疗前后GA和HbA1c进行对比研究,观察两者在妊娠期糖尿病治疗前后的变化。结果 B组空腹血糖、HbA1c和GA较A组高,差异有统计学意义,妊娠期糖尿病治疗前、后GA和HbA1c均有降低,但是差异无显著性。结论糖化白蛋白(GA)的测定对妊娠期糖尿病患者筛查诊断治疗有价值,可作为临床应用。Objective：Discussion Glycated albumin（GA） in the determination of diagnosis and treatment of gestational diabetes screening values,provide a reference for the clinical application of GA.Methods：Select 2009 1 months to August 2010 in our hospital for prenatal care in normal pregnant women（control group A）40 cases of pregnant women with abnormal glucose metabolism during pregnancy（B） in 40 patients fasting plasma glucose（FPG）,glycosylated hemoglobin（HbA1c） and GA,Group B patients on GA and HbA1c were compared before and after study,observed both before and after treatment in gestational diabetes mellitus change.Results： B fasting blood glucose,HbA1c and GA than the A group,the difference was statistically significant,gestational diabetes before and after treatment were lower GA and HbA1c,but the difference was not satistically significant.Conclusion：Glycated alvumin（GA）in the determination of diagnosis and treatment of gestational diabetes screening value can be used as clinical application.

关 键 词：糖化白蛋白 妊娠期糖尿病 糖耐量异常 糖化血红蛋白 

分 类 号：R714.256[医药卫生—妇产科学]