卡维地洛治疗慢性充血性心力衰竭的研究  

作　　者：王昭彬[1] 

机构地区：[1]吉林省辽源矿业集团总医院心内科,136200

出　　处：《中国社区医师（医学专业）》2011年第26期22-23,共2页

摘　　要：目的:探讨卡维地洛治疗慢性心力衰竭(CHF)的临床疗效。方法:收治CHF患者228例,随机分治疗组116例和对照组112例,治疗组在CHF标准治疗基础上,加用卡维地洛(2.5mg,2次/日开始逐渐递增至目标剂量,维持治疗),治疗前后分别评价心功能,左室射血分数(LVEF)。结果:经过卡维地洛治疗后,临床观察总有效率82.7%,明显优于对照值66.9%(P<0.05)。结论:在心衰治疗基础上应用卡维地洛安全有效,显著改善左室重塑。Objective：To observe the efficacy of carvedilol in the treatment of chronic heart failure（CHF）. Methods：228 CHF patients were randomly divided into the treatment group（n = 116） and the control group （n = 112）. On the basis of the conventional treatment, the treatment group was given carvedilol （ from 2. 5 mg, bid, and then added gradually to the maximum tolerated dose or target dose,and kept this dose）. After 12 months of treatment, the heart function and Left ventricular ejectfraction （LVEF） were observed in all cases. Results： After 12 months of treatment, the total effective rate of the treatment group（82.7% ） was higher than that of the control group（66.9% ） （P 〈 0. 05 ）. Conclusion： In the treatment of CHF, the curative effect of carvedilol combined with the conventional treatment is better than that of the conventional treatment, and carvedilol therapy can improve left ventricular performance, reveres LV remodeling.

关 键 词：卡维他洛 心力衰竭 充血性 

分 类 号：R541.61[医药卫生—心血管疾病]