持续性皮下胰岛素输注对初诊2型糖尿病患者胰岛β细胞功能及脂联素的影响  

作　　者：胡郁刚 陈根本[2] 

机构地区：[1]广东潮州市潮州医院,521000 [2]潮安县庵埠华侨医院,515638

出　　处：《中国社区医师（医学专业）》2011年第26期47-48,共2页

摘　　要：目的:观察短期持续皮下胰岛素输注对初诊2型糖尿病患者胰岛β细胞功能及脂联素的影响。方法:将35例初诊2型糖尿病患者随机分为治疗组和对照组。治疗组采用CSII,对照组仅皮下胰岛素注射。疗程均为2周,比较两组治疗前后胰岛β细胞功能指标和胰岛素抵抗变化。结果:两组AUCcp30、AUCcp120、脂联素等与治疗前对比均显著升高,且治疗组较对照组升高明显;而两组胰岛素抵抗指数均明显降低,治疗组降低较明显。结论:持续性皮下胰岛素输注,能快速提高初诊2型糖尿病患者胰岛β细胞第一时相胰岛素分泌和总量功能及脂联素水平,减轻胰岛素抵抗。Objective：Observation continuous subcutaneous insulin infusion patients with diagnosed type 2 diabetes, pancreatic β-cell function and adiponectin effects. Methods ： Treatment group CSII, control group only subcutaneous insulin injections. Changes were compared before and after treatment. Results：Two AUCcp 30 and AUCcp 120, adiponectin compared before treatment, significantly increased, treatment increased more significantly group;two groups signifi- cantly lower insulin resistance, treatment group significantly. Conclusion： Continuous subcutaneous insulin infusion can improve with type 2 diabetes insulin secretion and function total adiponectin levels, reduce insulin resistance.

关 键 词：持续性皮下胰岛素输注 2型糖尿病 Β细胞功能 脂联素 

分 类 号：R587.1[医药卫生—内分泌]