生肌玉红膏促进麻风足底溃疡肉芽生长及愈合的临床观察  

Clinical observation on promoting granulation tissue growth and healing of Shengji Yuhong plaster in patients with leprosy plantar ulcer

作　　者：石秀艳 周文生 姚昶[2] 

机构地区：[1]南京市疾控中心皮肤病性病专科医院皮肤科,231001 [2]江苏省中医院外科

出　　处：《中国临床研究》2011年第9期786-787,共2页Chinese Journal of Clinical Research

基　　金："十一五"国家支撑计划项目(2008BAI53B014)

摘　　要：目的观察生肌玉红膏在麻风足底溃疡治疗中的作用。方法将37例麻风足底溃疡患者按随机数字表法分成2组,治疗组19例,对照组18例。治疗组外用生肌玉红膏纱布,对照组外用凡士林纱布,隔日换药1次,疗程12周。每次换药记录溃疡的情况,对比创面肉芽生长积分疗效。结果治疗12周时,治疗组创面肉芽生长积分明显低于对照组〔创面肉芽性质积分:(1.15±0.89)vs(1.94±1.06)分,P<0.05;创面肉芽覆盖积分:(1.08±0.94)vs(1.89±1.02),P<0.05〕。治疗组与对照组的创面愈合率分别为47.37%、16.67%,总有效率分别为68.42%、33.33%,治疗组有增高趋势。治疗组用药期间未发生不良反应。结论采用生肌玉红膏治疗麻风足底溃疡疗效安全可靠,能明显改善创面微循环,促进肉芽生长,有利于提高溃疡愈合率。Objective To detect the effect of Shengji Yuhong plaster on leprosy plantar ulcer.Methods All 37 patients with leprosy plantar ulcer were randomly divided into treatment group（19 cases） and control group（18 cases）.Shengji Yuhong plaster gauze was used in the treatment group,and Vaseline gauze was used in control group.Dressing was changed every other day and the changs of ulcer were recorded.The course of treatment was 12 weeks.The growth grades of granulation tissue in two groups were compared.Results The qulity grades and coverage grades of granulation tissue in treatment group were lower than thoses in control group（1.15±0.89 vs 1.94±1.06,1.08±0.94 vs 1.89±1.02,all P〈0.05）.The healing rates of ulcer in treatment group and control group were 47.37% and 16.67%,and the total effective rates in two groups were 68.42% and 33.33% respectively.There were significant differences in healing rates and total effective rates in two group（all P〈0.05）.There were no adverse effects during treatment in treatment group.Conclusions The effect of Shengji Yuhong plaster for treating patients with leprosy planta ulcer is safe and relialble.Shengji Yuhong plaster can improve the microcirculation of wound and promote granulation tissue growth,and increase the healing rate of ulcer.

关 键 词：中医外治 生肌玉红膏 麻风病 足底溃疡 

分 类 号：R242[医药卫生—中医临床基础]