碱性离子液体催化含吲哚基噻唑酮衍生物的合成  

Synthesis of Thiazolinone Derivatives Containing Indolyl Group Catalyzed by Alkaline Ionic Liquid

作　　者：王俊岭[1] 马军营[1] 郝二军[2] 

机构地区：[1]河南科技大学化工与制药学院,河南洛阳471003 [2]河南师范大学化学与环境科学学院,河南新乡453002

出　　处：《化学世界》2011年第9期550-552,共3页Chemical World

摘　　要：以碱性离子液体[bmim]OH为溶剂和催化剂,由吲哚甲醛与2,4-噻唑二酮在80℃下反应50~60 min,以69.0%~83.5%的产率制备了四种噻唑酮衍生物。结果表明该方法简便易行,产率较高,所使用的离子液体对环境友好,并可循环使用。产物结构经1H NMR和IR确证。Four thiazolinone derivatives were synthesized by the condensation reaction of indole-3-carboxaldehydes with 2,4-thiazolinedione for 50~60 min with alkaline ionic liquid OH as dual solvent and catalyst the yield was from 69.0% to 83.5%,and the products were identified by 1H NMR and IR spectra.The proposed method is easy,efficient and highly yielding.The alkaline ionic liquid is environmental friendly and could be reused.

关 键 词：碱性离子液体 吲哚 噻唑二酮 合成 

分 类 号：O626.25[理学—有机化学]