小儿巨细胞病毒肺炎的临床分析  

Cytomegalovirus pneumonia in children in clinical analysis

作　　者：刘智聪[1] 

机构地区：[1]江苏省徐州医学院附属第三医院,221003

出　　处：《中外妇儿健康（学术版）》2011年第5期16-17,共2页

摘　　要：目的:探讨小儿巨细毒(CMV)肺炎的临床特点及诊断方法。方法:对55例经尿荧光定量PCR(Taqman探针技术)诊断为小儿巨细胞病毒肺炎病例的临床特点及治疗进行回顾性分析。结果:小儿CMV肺炎以婴幼儿多见,临床以咳嗽、喘息、发热、呼吸困难为主要表现,肺部多有干湿罗音,X线改变为肺纹理增多、斑点或斑片状影。予更昔洛韦治疗,痊愈43例、好转12例。结论:小儿CMV肺炎临床症状、体征、X线缺乏特异性,常合并其他病原体感染和肺外脏器受损,尿荧光定量PCR法是目前常用的快速、准确诊断CMV肺炎的实验室依据,更昔洛韦治疗有效。Objective：The present research is to investigate the clinical features and diagnostic methods for cytomegalovirus（CMV） pneumonia in children.Methods：55 children diagnosed of CMV pneumonia by fluorescence quantitative polymerase chain reaction of urine were analyzed retrospectively. Results：Cytomegalovirus pneumonia disease happened more frequently in small babies often seen with cough,asthma,fever and dyspnean,rales in the lungs and chest film shows interstitial changes are usually seen.All the patients have good results with Ganciclovir,among them,43 recovered and 12 improved.Conclusion：CMV pneumonia in children often lacks specific clinical features and fluorescence quantitative polymerase chain reaction for detection of Cytomegalovirus in urine is simple and convenient.Most of them have good results with Ganciclovir.

关 键 词：巨细胞病毒 肺炎 尿荧光定量PCR法 婴幼儿 

分 类 号：R725.6[医药卫生—儿科]