多糖改性聚乳酸的研究现状  

Research Status of Polysaccharides Modified Polylactide

作　　者：朱久进[1,2] 王远亮[2] 李军[1] 罗亚芳[1] 李刚[1] 

机构地区：[1]重庆理工大学化学化工学院,重庆400054 [2]重庆大学生物工程学院生物材料与仿生工程研究中心,重庆400044

出　　处：《材料导报》2011年第17期97-100,共4页Materials Reports

基　　金：国家自然科学基金(50603032);重庆市教委科学技术研究基金(KJ100815)

摘　　要：通过酯键相连的聚乳酸分子具有良好的可降解性,但疏水性强、缺乏生物活性使其应用受限。多糖及其衍生物分子具有大量的识别功能基团,可参与细胞的各种生命现象的调节,具有良好的生物相容性和可降解性,采用化学方式将多糖及其衍生物与聚乳酸材料相结合成为改善材料生物学性能最有效的方法之一。综述了多糖改性聚乳酸高分子材料的现状。Polylactide linked by ester bonds has favorable degradability, but its application is limited by its strong hydrophobicity and lack of bioactivity. With plentiful recognition functional groups, polysaccharide and its derivatives can participate in the adjustment of various cellular life phenomenon, and they have favorable biocompatibility and biodegradability, so it is one of the most effective method to immobilize polylactide with polysaccharide and its derivatives chemically to improve its performance. The research status of polysaccharides modified polylactide is reviewed.

关 键 词：聚乳酸 多糖 改性 

分 类 号：TQ225[化学工程—有机化工]