医务人员严重急性呼吸综合征幸存者康复期情绪、记忆和日常生活功能  

Emotional,memory and daily function among health care worker survivors with SARS

作　　者：石川[1] 于欣[1] 洪楠[2] 陈楚桥[3] 陈玉芳[1] 何毅[1] 

机构地区：[1]北京大学精神卫生研究所,卫生部精神卫生学重点实验室(北京大学),北京100191 [2]北京大学人民医院,北京101044 [3]中国科学院心理研究所,北京100101

出　　处：《中国心理卫生杂志》2011年第9期660-665,共6页Chinese Mental Health Journal

基　　金：985基金(985-2-027-39)

摘　　要：目的:调查医务人员严重急性呼吸综合征(SARS)幸存者康复期的情绪、记忆和日常生活功能,探讨心身交互作用关系。方法:采用前瞻性研究。方便取样抽取北京三家医院因感染新型冠状病毒而患SARS的医务人员43名,并选取年龄、性别、受教育程度匹配的对照组41名。对照组来自这三家医院的医务人员,用抑郁自评量表(SDS)评估抑郁,视觉模拟疼痛评定量表(VAS)评定疼痛,加州洛杉矶听觉词语学习测验(WHO-UCLA AVLT)及Rey-Osterrieth复杂图形测验(ROCF)评定记忆,日常生活能力量表(ADLS)评估日常生活功能。抑郁按严重指数(被试总分/80)分为轻中重三个等级。结果:医务人员SARS幸存者存在持续和显著的抑郁(轻、中、重度抑郁分别占31%、35%和17%)和疼痛,与对照组相比,存在更多的词语插入错误(P=0.047)。疼痛与情绪(r=0.40,P=0.031)和日常生活功能得分(r=0.47,P=0.01)显著正相关。甲基强的松龙治疗时间与日常生活功能得分显著正相关(r=0.38,P=0.041)。结论:抑郁及疼痛症状是SARS幸存者需要持续关注和处理的问题,在SARS治疗中长期大量使用甲基强的松龙应当慎重。Objective： To investigate the emotional, memory and daily function as well as psychosomatic re- lations of health care worker in Severe Acute Respiratory Syndrome （SARS） survivors. Method： A total of 43 health care worker SARS survivors and 41 healthy control subjects in three hospitals in Beijing were assessed de- pression with the Self-Rating Depression Scale （SDS）, pain with Visual Analogue Scale （VAS）, dally function with Activities of Daily Living Scale （ADLS）, and memory function with World Health Organization-University of Cali- fornia-Los Angeles Auditory Verbal Learning Test （WHO-UCLA AVLT） and Rey-Osterrieth Complex Figure Test （ROCF）. The depression was classified according to the severity index （ total score/80）. Results： The cohort expe- rienced lasting and striking depression （mild, moderate and severe depression were 31%, 35 % and 17% ） and pain （VAS = 5.2 ± 2. 2）. Compared with the healthy control group, SARS survivors had more intrusion errors （P = 0. 047）. Pain was positively correlated with emotion （r =0. 40, P =0. 031） and dally functioning （r =0. 47, P =0. 01）. The duration of methylprednisolone treatment was also positively correlated with daily functioning （ r = 0. 38, P = 0. 041 ）. Conclusion： Depression and pain are the major problems of SARS survivors which should be concerned about and handled to the physicians in general or infectious disease hospitals. Long-term utilization and overdosage of glucocorticoid are cautioned against in SARS treatment.

关 键 词：严重急性呼吸综合征 抑郁 疼痛 记忆 日常生活功能 前瞻性研究 

分 类 号：R563.8[医药卫生—呼吸系统] R749.41[医药卫生—内科学]