某省HIV阳性的静脉吸毒人群淋巴细胞免疫功能研究  

Study on the lymphocyte immunity function in intravenous drug users with HIV infection in certain area

作　　者：朱红艳[1,2] 欧阳红梅[1,2] 宋建新[1,2] 甸自金[1,2] 张芹[1,2] 蒋雅先[1,2] 

机构地区：[1]昆明医学院附属昆华医院 [2]云南省第一人民医院检验科,昆明650032

出　　处：《国际检验医学杂志》2011年第15期1686-1687,共2页International Journal of Laboratory Medicine

摘　　要：目的探讨人类免疫缺陷病毒(HIV)阳性的静脉吸毒者细胞免疫功能的变化。方法对静脉吸毒人员组成的HIV阳性组和HIV阴性组与健康对照组检测丙型肝炎病毒(HCV)感染率及淋巴细胞绝对值。结果 HIV阳性组和HIV阴性组HCV感染率分别是94.59%和82.93%;HIV阳性组T淋巴细胞亚群及自然杀伤(NK)细胞群均有不同程度的变化。结论 HIV阳性的静脉吸毒人群淋巴细胞免疫功能发生了不同程度的变化。Objective To explore the lymphocyte immunity function in intravenous drug users with HIV infection. Methods HCV infection and absolute counts of T-lymphocyte subsets were analyzed for intravenous drug users with or without HIV infec tion and healthy controls. Results The infection rates of HCV were 82.9% and 94.59% in HIV negative and HIV positive drug users respectively. There were changes of T-lymphocyte subsets and natural killer cells for different degree in HIV positive drug us ers. Conclusion There could be certain alternations of lymphocyte immunity function in HIV positive intravenous drug users.

关 键 词：HIV 静脉吸毒者 淋巴细胞免疫 

分 类 号：R512.91[医药卫生—内科学]