某地区呼吸道疾病患儿过敏原检测分析  

Detection and analysis of allergens in children with respiratory diseases in certain district

作　　者：周颖[1] 陈国千[1] 马坚[1] 高永辉[1] 

机构地区：[1]江苏省无锡市人民医院检验科,214023

出　　处：《国际检验医学杂志》2011年第14期1575-1576,共2页International Journal of Laboratory Medicine

摘　　要：目的了解无锡地区呼吸道疾病患儿的过敏原分布特点以及过敏原间的年龄差异。方法对呼吸道疾病患儿按年龄分成3组,即幼儿组(1~3岁)124例、幼童组(4~6岁)79例、儿童组(7~14岁)94例进行过敏原的分析。结果幼儿组以羊肉、牛奶、鱼、牛肉等食物组过敏原为主(阳性率分别为34.68%、39.52%、4.84%、34.68%),儿童组以户尘螨、点青霉、栎榆/梧桐等吸入性过敏原为主(阳性率分别为57.45%、39.36%、12.77%、27.66%、11.70%),其中户尘螨、羊肉、栎榆/梧桐的阳性率不同年龄组间差异均有统计学意义(P<0.05)。吸入性过敏原阳性率随患儿年龄增加而升高,食物性过敏原阳性率随年龄增加而降低。结论不同年龄组间患儿对某些特异性过敏原的过敏阳性率存在统计学差异,特异性过敏原检测实验可以帮助临床合理寻找呼吸道疾病患儿的相应过敏原并为其治疗提供依据。Objective To explore the distribution of allergens in children with respiratory diseases and to investigate the differ- ences of allergens positive rate and the sensitization severity between 3 different age groups. Methods From Nov. 2008 to Oct. 2009,297 children with respiratory diseases,in which 124 cases were 1 3 years old（i^fant~ group）, 79 were 4--6 years old（cheep- ers group） and 94 were 7--14 years old（elder children group）,were enrolled. C_~/i. _.,~ Jtil^rgens were measured hy serologic test. Results Allergy to foods as F88,F2, F3 and F27 was more common in infanta group（34. 68%, 39.52 %, 4.84%, 34.68 % ）, while allergy to inhalational allergens as D1, H1, E5, Tx4 and Mxl was moremen in elder children group （57. 45%, 39. 36%, 12.77% ,27.66% and 11.70%）. D1 and Tx4 of the infants group were lower and F88 was higher than those of elder children group （P〈0.05）. Conclusion The predominant causes of sensitization are inhalatlccao allergenam in elder children group,and food allergens in infants. The results of allergen based on children age should be anal）hind.

关 键 词：儿童 呼吸道疾病 过敏反应 

分 类 号：R725.6[医药卫生—儿科]