无溶剂条件下用于合成3,4-二氢嘧啶-2(1H)-酮的高效、可磁性回收Fe_3O_4纳米粒子催化剂(英文)  

Fe_3O_4 Nanoparticles as an Efficient and Magnetically Recoverable Catalyst for the Synthesis of 3,4-Dihydropyrimidin-2(1H)-ones under Solvent-Free Conditions

作　　者：Masoud NASR-ESFAHANI S. Jafar HOSEINI Fatemeh MOHAMMADI 

机构地区：[1]Department of Chemistry, Yasouj University

出　　处：《催化学报》2011年第9期1484-1489,共6页

基　　金：supported by Yasouj University Research Councils

摘　　要：The catalytic activity of Fe3O4 nanoparticles (NPs) in a one-pot three component condensation reaction consisting of an aromatic aldehyde, urea or thiourea, and a β-dicarbonyl under solvent-free conditions was investigated. This reaction affords the corresponding dihydropyrimidinones (thiones) in high to excellent yields. Compared with the classical Biginelli reactions this method consistently gives a high yield, easy magnetic separation, a short reaction time, and catalyst reusability.The catalytic activity of Fe3O4 nanoparticles （NPs） in a one-pot three component condensation reaction consisting of an aromatic aldehyde, urea or thiourea, and a β-dicarbonyl under solvent-free conditions was investigated. This reaction affords the corresponding dihydropyrimidinones （thiones） in high to excellent yields. Compared with the classical Biginelli reactions this method consistently gives a high yield, easy magnetic separation, a short reaction time, and catalyst reusability.

关 键 词：DIHYDROPYRIMIDINONES dihydropyrimidinthiones ferroferric oxide nanoparticle one-pot condensation SOLVENT-FREE 

分 类 号：O643.32[理学—物理化学]