经介入治疗女性冠心病患者术前血脂水平分析及与Syntax评分的关系  

Analysis for the blood lipid levels in female patients with coronary heart disease before percutaneous coronary intervention and the relationship between the blood lipid levels and Syntax score

作　　者：王永军[1] 周旭晨[2] 黄榕翀[2] 张妍[2] 佘在霞[3] 赵军魁[4] 石勇 马爱蕊[1] 

机构地区：[1]河北省胸科医院心内科,石家庄市050041 [2]大连医科大学附属第一医院心内科 [3]河北省邯郸市中心医院泌尿外科 [4]峰峰矿务局总医院ICU [5]河北省邱县人民医院心内科

出　　处：《河北医药》2011年第19期2902-2905,共4页Hebei Medical Journal

摘　　要：目的探讨行冠状介入治疗的女性冠心病患者术前血脂水平与冠状动脉Syntax评分的关系,为临床调脂治疗提供理论依据。方法回顾性调查行介入治疗女性冠心病患者246例。病例分为急性ST段抬高心肌梗死(STEMI)组56例和非ST段抬高心肌梗死(non-STEMI)组190例。根据syntax评分分为冠脉病变轻、中、重度3组,分别调查各组的术前血脂水平。结果 STEMI组较non-STEMI组:年龄偏大(P<0.05)、脑血管病史较多(P<0.05);Apo-A1和TG水平差异有统计学意义(P<0.05)。STEMI组各血脂成分在Syntax评分轻中重3组间差异无统计学意义(P>0.05)。non-STEMI组:LP(a)水平Syntax评分轻度病变组低于中度病变组(P<0.05);Apo-B/Apo-A1轻度病变组低于重度病变组(P<0.05);余各项血脂水平在3组间差异无统计学意义。结论 LP(a)和Apo-B/Apo-A1是女性冠心病(non-STEMI)患者较重要的血脂指标。Objective To evaluate the relationships between blood lipids levels and Syntax score in female patients with coronary heart disease （CHD） before percutaneous coronary intervention （PCI） in order to provide theoretical basis for regulating lipid treatment in clinic. Methods The data of 246 female patients with CHD before PCI were retrospectively analyzed. The patients were divided into STEMI group （ n = 56 ） and non-STEMI group （ n = 190）. According to the Syntax score, the patients were subdivided into 3 groups, light lesion group, moderate lesion group, and severe lesion group. The blood lipid levels before PCI were detected for all the groups. Results The mean age in STEMI group was significantly older than that in non- STEMI group （ P 〈 0.05）, and the proportion of cerebrovascular disease history in STEMI group was obviously higher than that in non-STEMI group （ P 〈 0.05）, and there were significant differences in the levels of ApoAl and TG between STEMI group and non- STEMI group （ P 〈 0.05）. However there were no significant differences in the blood lipid levels among light, moderate and severe groups of STEMI group （ P 〉 0.05 ）. As for non-STEMI group the levels of LP（a） in light lesion group were significantly lower than those in moderate lesion group （ P 〈 0.05 ）, and the levels of ApoB/ApoAI in light lesion group were significantly lower than those of severe lesion group （ P 〈 0.05 ）. Conclusion The LP（a） and Apo-B/Apo-AI are the important blood lipid indexes for female patients with CHD （non-STEMI）.

关 键 词：SYNTAX评分 血脂水平 冠心病 

分 类 号：R541.4[医药卫生—心血管疾病]