儿童再发性腹痛与幽门螺杆菌感染的关系及三联疗法的临床意义  

The Relationship between Recurrent Abdominal Pain and Heliobacter Pylofi Infection and Clinical Significance of Triple-Therapy in Children

作　　者：田玥[1] 朱宝[1] 王俊超[1] 肖翼春[1] 

机构地区：[1]南京医科大学附属无锡人民医院核医学科,江苏无锡214023

出　　处：《临床误诊误治》2011年第9期14-16,共3页Clinical Misdiagnosis & Mistherapy

摘　　要：目的探讨儿童再发性腹痛(recurrent abdominal pain,RAP)与幽门螺杆菌(Hp)感染的关系及三联疗法的临床意义。方法选择RAP患儿122例(RAP组),同期健康体检儿童62例(健康对照组),分别行13C-尿素呼气试验检测Hp,并对Hp阳性者予抗Hp三联根治性治疗。对两组Hp阳性率及清除率进行统计学分析。观察RAP组的疗效及不良反应。结果治疗前RAP组Hp阳性率高于健康对照组,差异有统计学意义(P<0.05)。治疗后两组Hp根除率比较差异无统计学意义(P>0.05)。治疗后RAP组中90例Hp阳性的患儿有效率为88.9%,不良反应发生率为30.3%。结论儿童RAP与Hp现症感染密切相关,三联疗法根除Hp临床效果好。Objective To explore the relationship between recurrent abdominal pain（RAP） and Heliobacter Pylofi（Hp） infection in children and investigate the clinical significance of tripe-therapy.Methods 122 children with RAP（RAP group）and 62 healthy children（healthy control group）were detected for Hp by 13-C-urea breath test,and Hp infected patients in both groups received radical treatment.The Hp infection rate and eradication rate in both groups were statistically analyzed,and effect rate and adverse reaction in RAP group were observed.Results Hp infection rate in RAP group was significant higher than that in healthy control group,and the difference was significant（P〈0.05）,while eradication ratio showed no significant difference between the two groups after Hp eradication therapy（P〉0.05）.The effect rate in 90 Hp-positive patients in RAP group was 88.9%,and the incidence rate of adverse reaction was 30.0%.Conclusion Children with RAP may be closely related to Hp infection,and triple therapy can eradicate Hp current infection effectively.

关 键 词：再发性腹痛 螺杆菌 幽门 儿童 

分 类 号：R725.7[医药卫生—儿科]