巨大硬膜型海绵窦海绵状血管瘤常规分次放射治疗的长期疗效  

Long term outcome of huge epidural type cavernous sinus cavernomas treated with conventionally fractionated radiotherapy

作　　者：邱晓光[1] 李少武[2] 陈怡东[3] 冯瑾[4] 

机构地区：[1]首都医科大学附属北京天坛医院放疗科,100050 [2]首都医科大学附属北京天坛医院神经影像中心,100050 [3]首都医科大学附属北京世纪坛医院放疗科,100038 [4]北京市普仁医院放疗科,100062

出　　处：《中国微侵袭神经外科杂志》2011年第9期395-397,共3页Chinese Journal of Minimally Invasive Neurosurgery

摘　　要：目的探讨常规分次放射治疗巨大硬膜型海绵窦海绵状血管瘤（CSC）的长期治疗效果。方法回顾性分析8例巨大颅中窝底硬膜型CSC的临床资料,均行常规分次放疗,总剂量为50 Gy。分析放疗后肿瘤体积变化,评价放射治疗的长期疗效。结果随访6~9年,肿瘤体积均呈进行性缩小并长期稳定。放疗后3年,所有病例肿瘤体积缩小达50%;放疗后5年,所有病例肿瘤体积缩小达80%。随访期间脑神经症状均有改善,无晚期放射性损伤。结论常规分次放射治疗可成为巨大硬膜型CSC的主要治疗方法之一。Objective To investigate the long term outcome of huge epidural type cavernous sinus cavernomas（CSC） treated with conventionally fractionated radiotherapy（CFRT）.Methods Clinical data of 8 patients with huge epidural type CSC in the middle cranial fossa were analyzed retrospectively.CFRT was performed in all the patients with a total dose of 50 Gy.The change of tumor volumes and long term outcome after radiotherapy were analyzed and evaluated respectively.Results During a follow-up period ranged from 6 to 9 years,the tumors volumes shrunk progressively and stabilized for long term.The tumor volumes reduction was achieved by 50% in 3 years after radiotherapy and by 80% in 5 years after radiotherapy.The neurologic symptoms improved in all the patients,and no radiotherapy-related complications were found during follow-up period.Conclusions CFRT can be one of the main treatments for huge epidural type CSC.

关 键 词：血管瘤 海绵状 中枢神经系统 海绵窦 放射外科手术 

分 类 号：R651.1[医药卫生—外科学]