中国美利奴羊CTNNB1基因SNP与羊毛直径关联分析  

SNP of CTNNB1 Gene and Its Association With the Wool Diameter Trait in Chinese Merino

作　　者：张艳花[1] 王力俭[1] 徐新明[1] 玛尔孜亚[1] 于丽娟[1] 拉扎提[1] 阿扎提[1] 周喜荣[1] 田可川[1] 

机构地区：[1]新疆维吾尔自治区畜牧科学院,乌鲁木齐830000

出　　处：《中国草食动物》2011年第5期8-10,共3页China Herbivores

摘　　要：以874只中国美利奴羊为研究对象,通过对与毛囊发生相关的CTNNB1基因SNP检测,应用SAS软件拟合线性模型,对CTNNB1基因SNP位点与羊毛直径性状进行关联分析。发现CTNNB1基因的819G>A、974A>G等2个位点与羊毛纤维直径显著相关,其中819G>A位点中,GA基因型对羊毛纤维直径是优势基因;974A>G位点中AA对羊毛纤维直径是优势基因型。上述结果为CTNNB1基因819G>A、974A>G位点作为细毛羊羊毛直径性状的分子标记提供了理论依据。874 Chinese Merino sheep were used to examine the SNP（single nucleotide polymorphism）of CTNNB1 gene.A G/A mutation was identified at position of 819GA in CTNNB1 gene,another A/G mutation was identified at position of 974AG.The effects of the mutations on the WFB（wool fiber diameter）traits were analyzed.The results showed that genotype GA was dominant for WFD at position of 819GA.The AA genotype of 974AG was the dominant genotype for WFD.The two mutations might be good markers for the wool fiber diameter of fine wool sheep

关 键 词：中国美利奴羊 CTNNB1 多态性 羊毛纤维直径 

分 类 号：S826.2[农业科学—畜牧学]