两亲性梳形共聚物PASP-Na-g-DDA的合成及接枝率对其水溶液胶束性质的影响  

PREPARATION OF AMPHIPHILIC COMB-POLYMER PASP-Na-g-DDA AND EFFECT OF GRAFTING LEVEL ON MICELLAR BEHAVIOR IN WATER SOLUTION

作　　者：孙婷[1] 杨伯涵[1] 李昆[1] 李亚鹏[1] 王静媛[1] 

机构地区：[1]吉林大学化学学院麦克德尔米德实验室,长春130023

出　　处：《高分子学报》2011年第10期1138-1143,共6页Acta Polymerica Sinica

基　　金：国家自然科学基金(基金号20904014);吉林省科技厅青年基金(基金号20080119);教育部青年资金(基金号2070310)资助项目

摘　　要：天冬氨酸自身缩聚产物聚琥珀酰亚胺(PSI)与十二胺(DDA)发生氨解反应,该氨解产物在碱性条件下水解,制得了一种两亲性梳形共聚物PASP-Na-g-DDA.通过改变DDA与PSI的比例,合成了一系列不同接枝率的两亲性梳形共聚物.用核磁共振(1H-NMR)及凝胶渗透色谱(GPC)对共聚物的结构进行了表征.随着疏水链段DDA在共聚物中比例的增加,分子量逐渐增加.研究了亲疏水比例对其水溶液性质的影响.结果表明,只有当疏水链段含量达到33.3%以上时聚合物才能形成胶束,并测试了此时聚合物的临界胶束浓度(CMC)值为1.259×10-3 mg/mL;用动态光散射(DLS)检测到,当DDA比例增加时,聚合物胶束的流体力学直径从136 nm减小到97 nm;用透射电镜(TEM)观察到胶束呈均匀球形.Poly（succinimide）（PSI）,obtained by polymerization of aspartic acid,reacted with dodecylamine（DDA） and then hydrolyzed under basic condition for preparing an amphiphilic comb-polymer PASP-Na-g-DDA.By varying the molar ratio of DDA and PSI,a series of polymers was synthesized with different grafting level of DDA.Then their structure was characterized by gel permeation chromatography（GPC） and 1H-nuclear magnetic resonance（1H-NMR）.The results showed that the targeted products were prepared successfully,and the molecular weight increased when the ratio of hydrophobic chains DDA increased.Also,it was studied that how the ratio of hydrophilic chains and hydrophobic chains affects the properties of the micelles formed by these polymers and it was revealed that only the percentage of hydrophobic chains reached up to 33.3% or above could the polymers form micelles;the critical micelle concentration（CMC） value of the polymer of which the grafting level was 33.3% was 1.259 × 10-3 mg/mL.The particle sizes of the micelles formed by the polymers were tested by dynamic light scattering（DLS）：along with increasing the ratio of DDA in the polymer chain,the hydrodynamic diameter of the micelles decreased from 136 nm to 97 nm;even spherical micelle was observed under transmission electron microscope（TEM）.

关 键 词：两亲梳形共聚物 接枝率 胶束 水溶液 

分 类 号：O631.3[理学—高分子化学]