葎草花粉变应原的研究进展与展望  

Research progress and prospects of Humulus pollen allergens

作　　者：孙秀珍[1] 吴媛媛[1] 

机构地区：[1]西安交通大学医学院第二附属医院呼吸内科,陕西西安710004

出　　处：《西安交通大学学报（医学版）》2011年第5期527-530,共4页Journal of Xi’an Jiaotong University（Medical Sciences）

基　　金：国家自然科学基金资助项目(No.30772010)~~

摘　　要：变态反应性疾病是世界范围内重大卫生问题之一,近50%的变态反应性疾病患者对草类花粉过敏。葎草在我国分布广泛,是引起花粉症的主要致敏物之一。葎草花粉症患者呈逐年上升趋势,已受到人们广泛关注。本文从葎草花粉的致敏状况、主要致敏蛋白组分、葎草花粉症诊断和治疗方法的建立以及主要变应原重组等方面进行综述。Currently,allergic diseases are a major worldwide health problem,and nearly 50% of them are caused by grass pollen allergy.Humulus is widely distributed in China,and its pollen is one of the main allergens that induce hay fever.The number of Humulus hay fever patients is increasing year by year,which has received widespread attention.This paper reviews the present situation of Humulus pollen allergy,the major allergenic protein components,the establishment of diagnosis and treatment for Humulus pollinosis,and the recombination of major allergens.

关 键 词：葎草花粉 重组变应原 低变应原性疫苗 

分 类 号：R562.25[医药卫生—呼吸系统]