人类免疫缺陷病毒感染早期患者的眼底改变  

Early fundus changes in patients with human immunodeficiency virus infection

作　　者：孙挥宇[1] 勇志鹏[2] 何宏宇[1] 李丹[1] 毛菲菲[1] 柳月红[1] 许雪静[1] 马爱民[1] 

机构地区：[1]首都医科大学附属北京地坛医院眼科,中国北京市100015 [2]北京仁和医院眼科,中国北京市102600

出　　处：《国际眼科杂志》2011年第10期1830-1831,共2页International Eye Science

基　　金：中国首都发展基金资助项目(No.2009-3155)~~

摘　　要：目的:了解人类免疫缺陷病毒感染患者的眼底改变。方法:对CD4≥200×106/L,不合并其他部位的机会感染和全身病,尚未曾接受高效抗逆转录病毒治疗的人类免疫缺陷病毒感染的患者进行眼底检查。结果:患者120例中114例(95%)患者的221眼(92.1%)的最佳矫正视力≥1.0;3例(2.5%)4眼(1.7%)视网膜后极部点片状出血者;1例(0.8%)患者1眼发现后极部棉绒斑。结论:视网膜微血管病变是人类免疫缺陷病毒感染患者的早期眼底改变,在CD4≥200×106/L时,病变发生机会较少,对视力无明显影响。AIM：To investigate fundus changes in patients infected by human immunodeficiency virus.METHODS：The study included 120 cases with an HIV infection that underwent ophthalmologic examinations.None of the patients has any systemic opportunistic infection and other system diseases found.The CD4＋ T lymphocyte counts were no less than 200×106/L.They didn＇t undergo highly active antiretroviral therapy.RESULTS：In all the 120 patients,the visual acuity in 114 cases（95%）of 221 eyes（92.1%） were no less than 1.0.Three cases （2.5%） of 4 eyes （1.7%） were found point and sheet bleeding in retinal posterior pole.1 case （0.8%）of 1 eye was found cotton-wool spots in the posterior pole.Retinal microvascular abnormalities were found in 4 cases （3.3%）.CONCLUSION：Retinal microvasculopathy is the early fundus changes of the patients infected by the immunodeficiency virus.It happened seldom when the CD4＋ T lymphocyte counts were no less than 200×106/L,and without significant effect on visual acuity.

关 键 词：人类免疫缺陷病毒感染 眼底改变 

分 类 号：R512.91[医药卫生—内科学]