应用瞬时波强负向波面积评估甲状腺功能亢进患者脑循环阻力  

Resistance of cerebral circulation in hyperthyroidism analysis using wave intensity with negative area

作　　者：吕静[1] 李秀兰[1] 王淑彬[1] 丁波[1] 邹丽[1] 

机构地区：[1]湖北江汉油田总医院超声影像科,湖北潜江433124

出　　处：《中国医学影像技术》2011年第9期1821-1824,共4页Chinese Journal of Medical Imaging Technology

摘　　要：目的探讨应用颈总动脉瞬时波强(WI)参数负向波面积(NA)评估甲状腺功能亢进症(HT)患者脑循环阻力的临床意义。方法 HT患者83例,其中49例游离三碘甲腺原氨酸(FT3)≤50 pmol/L(HT1组),34例FT3>50 pmol/L(HT2组);对照组为78名健康志愿者。应用WI技术检测受检者右侧颈总动脉,获得收缩早期正向波(W1)、收缩中期负向波面积(NA)、最大血流速度(Umax)等参数,并记录相关临床资料,对各组资料进行比较。结果①HT1组、HT2组W1、Umax明显高于对照组,差异均有统计学意义(P<0.001)。HT2组NA明显高于HT1组和对照组,差异均有统计学意义(P<0.001)。②各组NA值均随W1、Umax、脉压差(PP)的增高而升高(P<0.05),HT1组NA与FT3呈线性相关(P<0.05);HT2组NA与心率、收缩压(SP)呈线性相关(P<0.05)。③83例HT患者中,18例(21.69%)WI波形于收缩中期出现明显紊乱。结论 WI参数NA可反映HT患者脑循环阻力状态。Objective To evaluate the accommodation of cerebral circulation in patients with hyperthyroidism（HT） using wave intensity（WI）—negative area（NA）.Methods Totally 83 patients with HT were divided into two groups： HT1 group,n=49,with free triiodothyronine（FT3） ≤50 pmol/L and HT2 group,n=34,with FT3 50 pmol/L.Seventy-eight age matched normal subjects were enrolled（control group）.The parameters of WI—the first peak during early systole（W1）,NA during mid-systole and the maximum velocity（Umax） from right common carotid arteries were detected.Results ①The magnitude of W1 and Umax in HT1 and HT2 groups were considerably higher than those in control group（P0.001）.The magnitude of NA was considerably higher in HT2 group than that in control group and HT1 group（P0.001）.②NA increased with W1,Umax,pulse pressure（PP） considerably in all three groups（P0.05）.NA significantly correlated with FT3 in HT1 group（P0.05）,with systolic pressure（SP） and heart rate in HT2 group（P0.05）.③Eighteen of 83 patients with HT presented disorder waves in WI curves during mid-systole.Conclusion Common carotid arterial WI has the potential for evaluating the resistance of cerebral circulation with NA.

关 键 词：超声检查 甲状腺功能亢进 脑循环调节 瞬时波强 

分 类 号：R581.1[医药卫生—内分泌] R445.1[医药卫生—内科学]