危重症患者血清锌浓度的预后价值  

Prognostic Value of Blood Zinc Levels in Critically-ill Patients

作　　者：郑宇 陈朴 

机构地区：[1]浙江省乐清市人民医院,浙江乐清325600

出　　处：《中国现代医生》2011年第28期92-93,99,共3页China Modern Doctor

摘　　要：目的探索血清锌浓度水平是否与重症患者预后、ICU滞留时间、序贯器官衰竭估计(SOFA)评分等相关。方法纳入2009年1～3月进入ICU所有患者(年龄≥18岁)。记录患者人口学特征、ICU滞留时间、预后以及行SOFA评分。进入ICU 24h内采血检测锌浓度、C反应蛋白和蛋白浓度。结果共纳入36例患者。血锌和SOFA评分呈负相关。SOFA评分≥8血锌浓度明显低于SOFA评分<8的患者。结论在器官功能衰竭和重症患者中,血锌浓度明显下降,适量补充锌可能有助于患者恢复。Objective To investigate the hypothesis that a reduction in serum zinc levels among critically-ill patients is related to prognosis, length of stay in the ICU, sequential organ failure assessment （ SOFA ） scores. Methods This study included all the patients （ age 1〉 18 years ） entered ICU from January 2009 to March 2009. Patients＇ demographic features, SOFA scores, survival status, length of ICU stay were collected. Blood samples were collected within 24 hours after admission and analyzed for serum zinc, C-reactive protein and albumin levels. Results Total of 36 patients was included. Serum zinc concentrations were inversely correlated with SOFA scores. Patients with SOFA scores ≥ 8 had significantly lower serum zinc concentration compared with patients with SOFA scores 〈 8. Conclusion Serum zinc concentrations were decreased in organ failure and critical illness. Administration of zinc may be helpful for critically ill patients.

关 键 词：锌 器官功能衰竭 重症监护 

分 类 号：R459.7[医药卫生—急诊医学]