定量超声弹性成像技术对单发甲状腺结节的鉴别诊断  

Differential diagnosis of quantitative ultrasound elasticity imaging for solitary thyroid nodules

作　　者：崔可飞[1] 滑少华[1] 贺晓[1] 周元媛[1] 秦石成[1] 

机构地区：[1]郑州大学第一附属医院超声科,郑州450052

出　　处：《郑州大学学报（医学版）》2011年第5期709-711,共3页Journal of Zhengzhou University(Medical Sciences)

摘　　要：目的:探讨定量超声弹性成像技术对单发甲状腺结节的鉴别诊断价值。方法:162个单发甲状腺结节经病理分析,结节性甲状腺肿105个,腺瘤26个,腺癌31个,采用定量超声弹性成像技术检测其相对硬度,绘制ROC曲线。结果:结节性甲状腺肿、甲状腺腺瘤及癌的相对硬度分别为(1.191±0.208)、(1.326±0.295)和(2.094±0.754),3者比较,差异有统计学意义(F=68.360,P<0.001);甲状腺癌的相对硬度高于结节性甲状腺肿及甲状腺腺瘤(P<0.001),后两者差异无统计学意义(P>0.05)。以结节相对硬度诊断甲状腺良、恶性病变的ROC曲线下面积为0.901;以1.622作为界点,其敏感性、特异性及准确性分别为82.50%、95.40%和92.59%。结论:定量超声弹性成像技术对单发结节性甲状腺肿与甲状腺腺瘤的鉴别诊断能力不高,但对甲状腺癌具有很高的诊断价值。Aim：To research the differential value of quantitative ultrasound elasticity imaging for solitary thyroid nodules.Methods：Quantitative ultrasound elasticity imaging was used to detect the relative hardness of thyroid nodules from 162 patients with solitary thyroid nodules.ROC curve was also used to distinguish benign and malignant thyroid nodules according to the relative hardness.Results： There were significant difference in the relative hardness among solitary thyroid nodules,thyroid adenoma,and solitary thyroid cancer （F=68.360,P〈0.001）.The relative hardness of solitary thyroid cancer（2.094±0.754） was higher compared with those of solitary thyroid nodules（1.191±0.208） and thyroid adenoma（1.326±0.295） （P〈0.001）.Area under ROC curve for the differential diagnosis on benign and malignant lesions was 0.901.When the dividing value was 1.682,the sensitivity,specificity and accuracy for the differential diagnosis of quantitative ultrasound elasticity imaging was 82.50%,95.40% and 92.59%.Conclusion： The differential diagnosis abilities of quantitative ultrasound elasticity imaging for solitary thyroid nodules and thyroid adenoma is not remarkable,but very significant for solitary thyroid cancer.

关 键 词：超声弹性成像 甲状腺结节 相对硬度 鉴别诊断 

分 类 号：R653[医药卫生—外科学]