他汀序贯治疗对择期PCI患者围术期心肌保护作用的研究  

Statin therapy in Elective PCI in Patients with Perioperative Myocardial Protection Effect

作　　者：李满生 石高举 王会霞 蔡华 张晓华 李新峰 岳修宇 张领 

机构地区：[1]河南省平顶山市第二人民医院,河南平顶山467000

出　　处：《中国卫生产业》2011年第9期39-40,共2页China Health Industry

摘　　要：目的探讨他汀序贯治疗对择期经皮腔内冠状动脉介入治疗患者围术期心肌保护作用及他汀序贯治疗的安全性。方法对237例择期行PCI患者随机分为常规治疗组119例和他汀序贯治疗组118例,比较2组之间PCI术前、术后12hCK-MB、cTNT变化、术后30d主要心脏不良事件及主要不良反应。结果他汀序贯治疗组PCI术后12hCK-MB、cTNT、术后30d主要心脏不良事件低于常规治疗组(P<0.05),且无主要不良反应。结论他汀序贯治疗能减少择期PCI患者围术期心肌损伤,降低PCI术后主要心脏不良事件的发生,且安全有效。Objective To explore statin therapy in elective percutaneous transluminal coronary intervention in patients with perioperative myocardial protective effects of statin therapy and safety.Methods 237 patients undergoing PCI were randomly divided into routine treatment group 119 cases and statin sequential therapy group 118 cases,a comparison between the two groups PCI preoperative,postoperative changes in I2hCK--MB,cTNT,after 30 days of major adverse cardiac events and major adverse reaction.Results of statin sequential therapy group after PCI 12hCK-MB,cTNT,after 30 days of major adverse cardiac events than the conventional treatment group（P〈0.05）,and no major adverse reactions.Conclusion atorvastatin sequential treatment can reduce the elective PCI in patients with perioperative myocardial injury after PCl,reduced major adverse cardiac events,and safe and effective.

关 键 词：阿托伐他汀 经皮腔内冠状动脉介入治疗 心肌保护 

分 类 号：R541[医药卫生—心血管疾病]