低出生体质量儿神经行为发育及影响因素分析  

Analysis of Influence Factors and Neurobehavioral Development of Low Birth Weight Infants

作　　者：胡素君[1] 苏元元[1] 徐发林[1] 王玲[1] 李智睿[1] 程秀永[2] 

机构地区：[1]郑州大学第三附属医院儿内科,郑州450052 [2]上海交通大学医学院附属第三人民医院儿科,上海201900

出　　处：《实用儿科临床杂志》2011年第18期1439-1441,共3页Journal of Applied Clinical Pediatrics

基　　金：河南省教育厅科技攻关计划项目(2007320043)

摘　　要：目的探讨低出生体质量儿(LBWI)出生6个月、12个月时神经行为发育情况及影响因素。方法 2009年10月-2010年10月在本院出生后转入NICU的42例LBWI(LBWI组),同期在本院产科出生的健康足月新生儿(NBWI)51例(NBWI组),2组新生儿均于6个月、12个月时采用由中国科学院心理研究所和中国儿童发展中心(CDCC)合作制定的婴幼儿智能发育测验手册进行婴幼儿智能发育测试,比较智能发育指数(MDI)和心理运动发育指数(PDI),分析影响MDI和PDI神经行为发育的相关因素。调查内容包括姓名、性别、胎龄、日龄、出生体质量、娩出方式、家庭经济收入、父母文化程度、主要喂养方式、早期大小便训练、早期教育、游泳抚触等。结果 LBWI组在6个月时MDI和PDI与NBWI组比较差异均有统计学意义(t=2.893、2.082,P<0.01、0.05);LBWI组在12个月时MDI和PDI与NBWI组比较差异均有统计学意义(t=2.261、2.944,P<0.05、0.01)。回归分析显示,与MDI发育相关因素有胎龄、出生时体质量、娩出方式、家庭经济收入、父母文化程度、早期大小便训练、早期教育、游泳抚触。与PDI发育相关因素有出生时体质量、家庭经济收入、父亲文化程度、喂养方式、早期教育、游泳抚触。结论 LBWI组6个月、12月时神经行为发育仍落后于NBWI组,神经行为发育受多种因素影响。Objective To investigate the neurobehavioral development and the influence factors of low birth weight infant（LBWI） in 6 month and 12 month after birth. Methods Forty-two LBWI（LBWI group） deliveried from Oct.2009 to Oct.2010 were enrolled in Newborn Intensive Care Unit（NICU）,the Third Affiliated Hospital of Zhengzhou University.Fifty-one normal birth weight infant（NBWI）（NBWI group） born in Obstetrics of the Third Affiliated Hospital of Zhengzhou University,from the same period.Infants of 2 groups received children′s development center of China（CDCC）with infant intelligence development inspection manual made by Institute for Psychological Research,Chinese Academy of Sciences and CDCC for cooperation at the 6th month and 12th month after birth.Physical development index（MDI）and psy-chomotor development index（PDI）and the influence factors on the MDI and PDI between 2 groups were compared.The content of survey included name,sex,gestational,day age,birth weight,style of childbirth,income of family,cultural degree of parents,feeding types,early urine training,early education,swimming and touching,etc. Results There were statistically significant difference between LBWI group and NBWI group in MDI and PDI at the 6th month（t=2.893,2.082,P0.01,0.05）.There were statistically significant difference between LBWI group and NBWI group in MDI and PDI at the 12th month（t=2.261,2.944,P0.05,0.01）.Regression analysis showed that the MDI factors associated with development were gestational,birth weight,style of childbirth,income of family,cultural degree of parents,early urine training,early education,swimming and touching.And the PDI factors associated with development were birth weight,family income,cultural degree of father,feeding types,early education,swimming and touch. Conclusion The development of neurobehavioral of group LBWI is inferior to group NBWI at the 6th month and 12th month after birth,and is influenced by various factors.

关 键 词：低出生体质量儿 神经行为 影响因素 

分 类 号：R722.1[医药卫生—儿科]