谷氨酸和谷氨酰胺转运系统的研究进展  

Recent Advances in Transport Systems of Glutamate and Glutamine

作　　者：王秋菊[1] 许丽[1] 范明哲[2] 

机构地区：[1]东北农业大学动物科技学院动物营养与饲料系,哈尔滨150030 [2]圭尔夫大学安大略农业学院动物与家禽科学系

出　　处：《动物营养学报》2011年第6期901-907,共7页CHINESE JOURNAL OF ANIMAL NUTRITION

基　　金：加拿大自然科学研究基金(OMAFRA);国家留学基金(2008661002)

摘　　要：谷氨酸作为幼年动物重要的氨基酸,是肠内能量生成的最大贡献者,它不能由机体自身合成,需额外添加或通过谷氨酸前体物谷氨酰胺转化而成。谷氨酸是谷胱甘肽合成的重要底物,对动物肠道抗氧化剂的提供有重要作用,其转运依靠谷氨酸转运载体完成。因此,本文就谷氨酸和谷氨酰胺转运系统的分类及作用机制做一综述。Glutamate is the largest contributor to intestinal energy generation as an essential amino acid for young animal growth,and it is obtained from diets or transformed from glutamine because it cannot be synthesized in vivo.Glutamate is an important substrate for glutathione synthesis and plays a critical role in supplying intestinal antioxidants,and its transporters are responsible for removing glutamate from the extracellular space.Functions and characteristics of glutamate and glutamine transport systems are reviewed in this article.

关 键 词：谷氨酸 谷氨酰胺 转运载体 作用机制 

分 类 号：S811.2[农业科学—畜牧学]