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作 者:王银河[1] 朱丽华[1] 俞杨[1] 王斌[1] 邱勇[1]
机构地区:[1]南京大学医学院附属鼓楼医院骨科,江苏省南京210008
出 处:《中国基层医药》2011年第21期2881-2882,共2页Chinese Journal of Primary Medicine and Pharmacy
摘 要:目的观察奇正消痛贴膏联合仙灵骨葆治疗膝骨关节炎(KOA)的疗效及安全性。方法KOA患者70例随机分成两组。治疗组外敷奇正消痛贴膏联合口服仙灵骨葆治疗。对照组双氯芬酸乳胶剂2-4g涂患处。结果治疗组按WOMAC骨关节炎指数评分结合5点口述评分法评价疗效,总有效率80.0%,与对照组77.10%差异无统计学意义(X^2=1.21,P〉0.05)。用药期间未发现不良反应。结论外用奇正消痛贴膏联合仙灵骨葆治疗KOA可有效改善患者疼痛及活动受限症状,效果满意。Objective To compare and observe the clinical effect of Qizhengxiaotong plaster and Votalin e-mulsion in curing osteoarthritis of knee(KOA) for outpatient treatment. Methods In 70 cases ,the KOA patients are randomly divided into treatment group and control group, respectively given Qizhengxiaotong plaster 151us Xianling Gubao and Votalin emulsion for one month. To observe the clinical effects of patients respectively pre and post treat- ment. Results After a course of treatment, Qizhengxiaotong plaster plus Xianling Gubao could improve the clinical symptoms and signs significantly. Its improvement for pain was the same as Votalin. But Qizhengxiaotong plaster plus Xianling Gubao was significantly better than Votalin in eliminating the swollen, tenderness and dysfunction. And there was no obvious difference between Qizhengxiaotong plaster plus Xianling Gubao and Votalin emulsion in total effective rate, evaluated by WOMAC Osteoarthritis Index Guide. and VRS-5. The typical symptoms were improved after the therapeutic method. No adverse reaction was found during the treatment. Conclusion Qizhengxiaotong plaster plus Xianling Gubao had obvious effect on the osteoarthritis of knee and could improve the patients' pain and limitation of activity. Hence ,it was worthy to be generalized in the conservative treatment of the osteoarthritis of knee for out-patients.
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