慢性粒-单核细胞白血病合并Sweet综合征转化为急性白血病一例并文献复习  

Chronic myelomonocytic leukemia complicated with Sweet＇s syndrome developed into acute myelomonocytic leukemia： a case report and review of the literature

作　　者：王加菊[1] 张翼鷟[1] 

机构地区：[1]天津医科大学附属肿瘤医院血液内科,300060

出　　处：《白血病．淋巴瘤》2011年第9期554-556,共3页Journal of Leukemia & Lymphoma

摘　　要：目的提高对慢性粒．单核细胞白血病（CMML）合并Sweet综合征的认识。方法回顾性分析1例CMML合并皮肤疱疹患者资料，取皮肤活检进行病理检测，并给予DA、CAG方案等化疗。结果病理诊断为CMML合并Sweet综合征，单用皮质激素治疗效果不佳，CAG方案使CMML获得完全缓解，皮疹得到有效控制。3个月后Sweet综合征复发，CMML进展为急性单核细胞白血病。结论CMML合并Sweet综合征罕见，高度提示短期内进展为急性白血病。Objective To improve the understanding of chronic myelomonocytic leukemia associated with Sweet＇ s syndrome. Methods Retrospective analysis of a case of chronic myelomonocytic leukemia associated with skin herpes was reported. Skin biopsy was performed. DA and CAG regiment were administrated. Results Sweet＇s syndrome was diagnosed by skin biopsy. Corticosteroids therapy alone was not effective. Complete remission was achieved by CAG regiment and skin rash has been effectively controlled. Three months later Sweet＇ s syndrome relapsed and chronic myelomonoeytie leukemia developed into acute myelomonocytic leukemia. Conclusion Chronic myelomonocytic leukemia associated with Sweet＇s syndrome is rare but implies a quick progression to acute myelomonocytic leukemia.

关 键 词：白血病 粒-单核细胞 慢性 SWEET综合征 白血病 粒.单核细胞 急性 

分 类 号：R733.7[医药卫生—肿瘤]