大黄联合黄芪治疗慢性肾衰竭的临床研究  

Clinical analysis of Rhubarb and Astragalus cure patients with chronic renal failure

作　　者：梁庆丰[1] 张洁[1] 冯涛[1] 刘永富[1] 马慧玲[1] 格日勒[1] 潘冰[1] 边春燕[1] 赵洪[1] 

机构地区：[1]包头医学院第二附属医院肾内科,内蒙古包头014030

出　　处：《疾病监测与控制》2011年第10期631-632,共2页Journal of Diseases Monitor and Control

摘　　要：目的对中药黄芪联合大黄在慢性肾功能衰竭中的作用进行临床观察和研究。方法将非透析治疗的慢性肾衰竭病人共60例随机分成两组,每组30例。在纠正其他可逆因素的基础上治疗组加用黄芪和大黄30d,观察病人BUN Scr及24h尿蛋白定量变化。结果 (1)治疗组和对照组治疗后显BUN Scr有明显下降,但对两组治疗后BUN Scr下降差值观察,治疗组明显优于对照组(P<0.01)。(2)治疗组24h尿蛋白下降以及血浆白蛋白提高均较对照组显著改变(P<0.05),(P<0.01)血脂降低两组变化不大,差异无统计学意义(P>0.05)。结论 (1)大黄联和黄芪治疗慢性肾衰竭在一定程度上可促进毒素排泄,延缓肾衰,减少尿蛋白,改善低蛋白血症。(2)大黄配伍黄芪对血脂的作用有待进一步观察。objective to analyse and research the clinical characteristics when Rhubarb and Astragalus apply to the care of chronic renal failure. Methods The sixty chronic renal failure patients didn＇t care by hemodialysis were divided into two groups averagely. Based on the rectifing other reversible factors, Rhubarb and Astragalus were apply to cared group thirty days and wacth the change of BUN Scr and24 hour proteinnuvia of patients. Results （1） BUN Scr of two groups declined significantly after curing. But cured group is better than control group by watching the decline of tow groups. （2） The decline of 24-hour proteinuria and the increasing of plasma Albumin of cured group had a significant change（P^0.05）. （P〈0.01）. The lipidenmia＇s decline of two groups hadn＇t a significant difference（P^0.05）. Conclusions （1） Rhubarb and Astragalus can propel the release of toxin, delay kidney disease, decrease proteinuvia and improve hypopmteinemia. （2） The effect that Rhubarb and Astragulus Care hyperlipipemia need analyse in future.

关 键 词：大黄 黄芪 慢性肾衰竭 

分 类 号：R692.5[医药卫生—泌尿科学]