川白芷药材中有机磷类农药残留量的测定  

Analysis of organophosphorus pesticides residues in Angelica dahurica

作　　者：蒲道俊 喻强[2] 李铁钢[3] 瞿显友[2] 张宝喜[3] 罗维早[2] 

机构地区：[1]西南药业有限公司,重庆495216 [2]重庆市中药研究院,重庆400065 [3]成都中医药大学,四川成都611730

出　　处：《华西药学杂志》2011年第5期483-486,共4页West China Journal of Pharmaceutical Sciences

基　　金：国家科技支撑计划项目(2007BAI40B03)

摘　　要：目的制定川白芷药材中有机磷类农药最大残留的限量标准(MRLs)。方法采用乙酸乙酯冰浴超声提取,SPE活性炭固相萃取柱净化除杂质,GC-NPD法检测药材中有机磷类农药的残留量。结果建议将川白芷药材中有机磷类农药的最大残留限量规定为:敌敌畏0.2μg.g-1、乙酰甲胺磷0.5μg.g-1、乐果0.2μg.g-1、马拉硫磷0.5μg.g-1、杀扑磷2.0μg.g-1、二嗪农0.2μg.g-1、乙硫磷0.5μg.g-1、氧化乐果0.05μg.g-1,甲胺磷、甲基对硫磷、久效磷、对硫磷不得检出。结论有机磷农药残留的检测可为生产绿色中药和保障用药安全提供科学依据。OBJECTIVE To establish the MRLs of organophosphorus pesticides residues（OPPs） in Angelica dahurica.METHODS The sample was extracted by ice sonication with ethylacetate and purified with SPE,followed by detection using GC-NPD.RESULTS The maximum residue limits of Methamidophos,Dichlorovos,Acephate,Omethoate,Monocrotophos,Dimethoate,Diazinon,Parathion-methyl,Malathion,Parathion,Methidathion,Ethion were 0,0.2,0.5,0.05,0,0.2,0.2,0,0.5,0,2.0,0.5 μg·g-1,respectively.CONCLUSION This research provides scientific basis for production of green Chinese herbs and ensures the safety in utilization of drugs.

关 键 词：川白芷药材 有机磷类农药 气相色谱法 最大残留限量 

分 类 号：R917[医药卫生—药物分析学]