膜过滤对栀子提取液中环烯醚萜类成分的影响  

Effect on Iridoid Components of Extract from Gardeniae Fructus by Membrane Filtration

作　　者：张鹏[1] 孟硕[1] 刘建勋[1] 

机构地区：[1]中国中医科学院西苑医院实验研究中心,北京100091

出　　处：《中国实验方剂学杂志》2011年第19期1-3,共3页Chinese Journal of Experimental Traditional Medical Formulae

基　　金：国家自然科学基金(30772755);国家科技重大专项(2009ZX09103-317)

摘　　要：目的:研究栀子水提液超滤膜过滤后含量和相对黏度的变化。方法:利用乌氏黏度计测量栀子水提液在不同密度、通过不同截留相对分子质量超滤膜处理后相对黏度的变化,考察超滤对去乙酰基车叶草苷酸甲酯、京尼平-1-β-D龙胆双糖苷、栀子苷3个成分的影响。结果:随着滤膜孔径的减小及药液相对密度的增加,各成分的损失率均有增大的趋势;超滤后栀子提取液的相对黏度明显降低,随着滤膜孔径及提取液相对密度的减小,超滤液的相对黏度也有所降低。结论:栀子水提液超滤后能显著降低相对黏度。Objective：To study on the change of content and intrinsic viscosity from water extract of Gardeniae Fructus by ultrafiltration.Method：Different relatively density was determined by Ubbelohde viscometer.Investigated the change of intrinsic viscosity by dealed with ultrafiltration of different retention molecular weight,then study on the effect of deacetyl-asperulosidic acid methyl ester,genipin-1-β-D-gentiobioside and geniposide by ultrafiltration.Result：With the pore size decreased and relative density increased,the loss rate of components have a tendency to increase;Relative viscosity of extract from Gardeniae Fructus reduced significantly after ultrafiltration,with the membrane pore size and extract the relative density decreased,the relative viscosity of ultrafiltrate also decreased.Conclusion：Viscosity of water extract from Gardeniae Fructus decreased significantly after ultrafiltration.

关 键 词：超滤 栀子 相对黏度 

分 类 号：R283.6[医药卫生—中药学]