寒痹贴的提取工艺优选  

Study on Extraction Technology of Hanbi Patch

作　　者：段晓颖[1] 平佳宜[2] 孙广科[1] 

机构地区：[1]河南中医学院第一附属医院,郑州450000 [2]河南中医学院,郑州450008

出　　处：《中国实验方剂学杂志》2011年第19期38-40,共3页Chinese Journal of Experimental Traditional Medical Formulae

摘　　要：目的:优选寒痹贴的最佳提取工艺。方法:草乌以总生物碱的提取量为考察指标,采用正交试验优选醇提工艺;赤芍等6味中药以芍药苷的提取量为考察指标,采用正交试验优选水煎工艺。结果:寒痹贴的最佳提取工艺为草乌加70%乙醇6倍,回流2次,每次2 h;赤芍等药材加水8倍量,煎煮3次,每次1 h。结论:优选出的提取工艺合理、可行,为其生产提供了科学依据。Objective：To optimize the best extraction technology of Hanbi patch.Method：Orthogonal test was used to optimize alcohol extraction process of Aconiti Kusnezoffii Radix with the yield of total alkaloid as index;Optimize decocting technology of Paeoniae Radix Rubra and other five herbs by orthogonal design with the extraction amount of paeoniflorin as index.Result： The optimum extraction technology was as follows：Aconiti Kusnezoffii Radix was refluxed with 6 times amount of 70% ethanol for two times by 2 h per time.Paeoniae Radix Rubra and other herbs was added 8 times amount of water for three times with 1 h each time.Conclusion：The optimized extraction process is reasonable,feasible and provide scientific basis for the production.

关 键 词：寒痹贴 提取工艺 正交试验 总生物碱 芍药苷 

分 类 号：R283.6[医药卫生—中药学]