糖尿病血管并发症的中药防治  

Effects of Chinese Medicine on Vascular Complication of Diabetes Mellitus

作　　者：邬伟魁[1] 张海燕[1,2] 宋伟[1] 芦乾[1] 刘昊[1] 贺娅[1] 郑琴[1] 杨明[1,3] 

机构地区：[1]江西中医学院现代中药制剂教育部重点实验室,南昌330004 [2]西南交通大学材料先进技术教育部重点实验室,成都610003 [3]成都中医药大学,成都611137

出　　处：《中国实验方剂学杂志》2011年第19期292-296,共5页Chinese Journal of Experimental Traditional Medical Formulae

基　　金：中医药行业科研专项项目(200708006);"十一五"重大新药创制重大专项(2009ZX09103-393;2009ZX09310-005)

摘　　要：对糖尿病(diabetes mellitus,DM)血管并发症的中药防治研究进行文献整理和分析。介绍了中药用治微血管并发症(糖尿病性肾病、糖尿病视网膜病变)及中药复方(片剂、注射液、汤剂)、单味药及提取部位(大黄、薏苡仁多糖、苦碟子注射液、山茱萸环烯醚萜总苷)和单体成分(丹酚酸A、葛根素、栀子苷、柚皮苷及黄芪甲苷)在DM大血管并发症防治中的应用研究,包括其临床观察、动物在体研究和体外细胞实验,以期发掘中药在治疗中的优势,为糖尿病治疗的中药应用和新药研发提供参考。在DM血管并发症的治疗药物中,中药因其多成分、多途径、多靶点作用而显示出独特的优势。Literatures aboutpreventing vascularcomplication of diabetes mellitus（DM）have beenanalyzed.There aremore and more DM patients with DM vascular complications,which has been paid attention for its big damage.Traditional Chinese medicine shows its characteristics and advantages in DM treatment.Its applicationisgrowing concern.This articlemainlyreviews the traditional Chinese medicine（tablets,injection,decoctions）,single herb withextracts（pieplant,coix seed,ect.）,and monomer components（salvianolic acid,puerarin,geniposide,naringin and astragaloside）in the prevention and treatment of vascular complications of DM（diabetic nephropathy and diabetic retinopathy）,including clinical observations,animal studies in vivo and in vitro experiments.Aiming to explore the advantages of Chinese medicine in the treatmentof DM,andimprove itsapplicationin theresearch of DM and new drug development.

关 键 词：糖尿病 消渴 血管并发症 中药 

分 类 号：R287[医药卫生—中药学]