儿童不典型川崎病的临床分析  

CLINICAL ANALYSIS OF ATYPICAL KAWASAKI DISEASE IN CHILDREN

作　　者：廖先华[1] 许玉霞[1] 

机构地区：[1]四川省川北医学院附属医院儿科,南充637000

出　　处：《现代预防医学》2011年第20期4150-4151,4155,共3页Modern Preventive Medicine

摘　　要：[目的]分析儿童不典型川崎病的临床特点，为能尽早明确诊断提供依据。[方法]对。2006年6月-2010年6月在我院诊断的49例不典型川崎病患儿的临床表现及实验室检查指标进行回顾分析，并与同期的143例典型川崎病进行比较。[结果]49例不典型川崎病均有发热，其中持续5d以上发热者47例（95．9％）。除发热外其他临床表现以眼结膜充血和口唇黏膜改变发生率最高，分别为89．8％和81．6％。实验指标中以血沉增快、外周血白细胞升高、CRP增高的发生率较高，分别为89．9％、85．7％、81．1％，常伴有血红蛋白和血浆白蛋白降低，与典型川崎病具有一致性。[结论]不典型川崎病早期表现隐匿，临床医师应具有对本病的警惕性，进行周密的临床观察，结合实验室检查综合分析，以求早诊断、早治疗，减少冠状动脉的损伤。对不明原因的发热，实验检查血沉增快，CRP增高，外周血自细胞升高，血红蛋白降低，血浆白蛋白降低，血钾、血钠水平降低可作为诊断不典型川崎病的参考指标。[Objective] To study the clinical features in children with a.typical Kawasaki disease （KD）. [Methods! From June of 2006 to June of 2010, 192 KD were diagnosed in hospitalized children ; 49 were atypical KD. Retrospective anal- ysis was made in the clinical manifestations and the changes of experimental indicators. [Results] 49 atypical KDhad fever; Fever More than 5 days was 47. Besides fever, the highest rate was eye conjunctiva congestion and mucosal chapped lips. Ery- throcyte sedimentation rate （ESR） added fast, white blood cell （WBC） increased, c-reactive protein （GRP） heighten, these were also common. Moreover, hemoglobin （HB） and serum albumin （ALB） were often reduced. These features were consistent with typical KD. [Conclusion] Atypical KD concealed inchoate expression. In order to clear diagnosis early, clinicians should cope with clinical and experimental inspection comprehensive analysis. ESR add fast, CRP heighten, WBC increase, HB and ALB reduce, Potassium and sodium levels drop can serve as reference index to diagnosis atypical KD.

关 键 词：川崎病 诊断 儿童 

分 类 号：R729[医药卫生—儿科]