PEG-400中三组分一锅法合成1-芳基苯并[f]喹啉衍生物  

Three-component one-pot synthesis of 1-aryl-4-benzo[f]quinoline derivatives in PEG-400

作　　者：王喜存[1] 王雪梅[1,2] 权正军[1] 张彰[1] 

机构地区：[1]西北师范大学化学化工学院,甘肃兰州730070 [2]兰州理工大学机电工程学院,甘肃兰州730050

出　　处：《西北师范大学学报（自然科学版）》2011年第5期60-63,73,共5页Journal of Northwest Normal University(Natural Science)

基　　金：甘肃省高分子材料重点实验室基金资助项目

摘　　要：以芳醛、2-萘胺和Meldrum酸为原料,在回流条件下以低分子量的聚乙二醇(PEG-400)为有机反应溶剂和催化剂,通过三组分一锅法反应,合成了一系列1-芳基苯并[f]喹啉衍生物.该法具有反应条件温和、产率较高、后处理简单、环境友好等优点,符合绿色化学的要求.A series of 1-aryl-1,2-dihydrobenzo[f]quinolin-3（4H）-one derivatives are synthesized by a three-component one-pot reaction of benzaldehyde,naphthalene-2-amine and Meldrum acid at refluxing temperature,in which PEG-400 is served as catalyst and solvent.This method has the advantages of milder reaction conditions,good yields,simple working-up procedure and environmental benignity,it is in accordance with the needs of green chemistry.

关 键 词：一锅法 苯并[f]喹啉 PEG-400 

分 类 号：O626.32[理学—有机化学]