活血益气法对气滞血瘀证2型糖尿病大鼠治疗的实验研究  

The Experiment Research on Qi Stasis Plus Blood Stasis Diabetic Rat Models with Active-blood Soup and yiqi-vein's Method

作　　者：陈嘉斌[1] 柴可夫[1] 张副兴[1] 吕帅洁[1] 郑杨[1] 柴可夫(指导) 

机构地区：[1]浙江中医药大学,浙江杭州310000

出　　处：《中华中医药学刊》2011年第10期2228-2230,共3页Chinese Archives of Traditional Chinese Medicine

基　　金：浙江省教育厅浙江省大学生科技创新活动计划(新苗人才计划)立项资助项目(67401129)

摘　　要：目的:研究活血益气法对于气滞血瘀证型2型糖尿病大鼠模型的治疗作用。方法:对大鼠用针刺激[1]及高脂高糖饮食[2]建立气滞血瘀证型。后给予大鼠日照并灌胃脂肪乳10日后尾静脉一次性注射四氧嘧啶(80mg/kg)建立2型糖尿病模型。采用血府逐瘀汤加生黄芪怀山药进行治疗并检测指标。结果:通过血液流变学指标,血糖等客观指标分析,模型建立可靠,气滞血瘀证型2型糖尿病大鼠各指标明显好转。结论:使用针刺及高脂喂食建立模型可为将来2型糖尿病中医研究提供实验基础,活血益气法治疗气滞血瘀证2型糖尿病具有较好的疗效,但用药需谨慎配伍。Objective： To study the effect on Qi stasis plus blood stasis diabetic rat models by Active-blood soup and yiqi-vein＇s method.Methods：The Qi stasis plus blood stasis diabetic rat models were made by electroacupuncture stimulation and high-sugar-fat-diet.Then give them Fat Emulsion and sunlight for 10 days before injecting one-off Alloxan monohydrate on the vein of tail.Give the treatment with Active-blood soup and yiqi-vein＇s method and record the index.Results：According to the analysis of hemorheology indices and glucose objective index,it turns out that the models are reliable.The rat＇s indexes improve.Conclusion Setting Qi stasis plus blood stasis diabetic rat models up will offer new experimental basis for the studies in the future.The treatment,Qi stasis plus blood stasis diabetic mellitus with Active-blood soup and yiqi-vein＇s method,has good effectiveness,we should be careful with the traditional Medicine compatibility.

关 键 词：活血益气法 气滞血瘀证型 动物模型 四氧嘧啶 

分 类 号：R587.1[医药卫生—内分泌]