河南地区596例矮小症病因分析  

Etiologic analysis of short stature in 596 children in Henan

作　　者：刘慧娟[1] 李桂玲[1] 高丽[1] 王霞[1] 

机构地区：[1]河南省人民医院儿科,郑州市450003

出　　处：《中华实用诊断与治疗杂志》2011年第9期844-845,共2页Journal of Chinese Practical Diagnosis and Therapy

摘　　要：目的探讨河南地区儿童矮小症的病因。方法设计统一调查表,采集596例0~19岁矮小症患儿病史、身高、体质量、父母身高及青春期发育史,实验室检查结果,并进行病因诊断。结果 596例矮小症患儿中生长激素缺乏症279例（46.81%）,特发性矮小症122例（20.47%）,体质性生长及青春期延迟44例（7.38%）,特发性中枢性性早熟41例（6.88%）,甲状腺功能低下29例（4.87%）,Turner s综合征21例（3.52%）。不同病因矮小症患儿低出生身长及低出生体质量发生率比较,差异无统计学意义（χ2=1.27,P〉0.05）。结论河南地区儿童矮小症以生长激素缺乏症和特发性矮小症多见,出生参数不能决定未来矮小状态。Objective To survey the etiology of short stature in children in Henan.Methods A total of 596 patients with short stature,aged from 0 to 19 years,were investigated.A questionnaire was defined including disease history,body mass and height,parent＇s height,pubertal development and laboratory examination to analyze the etiology.Results Among 596 cases of short stature,there were growth hormone deficiency in 279 cases（46.81%）,idiopathic short stature in 122 cases（20.47%）,constitutional delay of growth and puberty in 44 cases（7.38%）,idiopathic central precocious puberty in 41 cases（6.88%）,hypothyroidism in 29 cases（4.87%） and Turner＇s syndrome in 21 cases（3.52%）.There were no significant differences in the incidence rates of low birth-weight and low birth-length among children with different etiology（χ2=1.27,P0.05）.Conclusion Growth hormone deficiency and idiopathic short stature are the common causes of short stature in Henan.The birth parameters are not correlated with short stature.

关 键 词：矮小症 儿童 病因分析 

分 类 号：R725.8[医药卫生—儿科]