双水平气道正压通气呼吸机治疗慢性阻塞性肺疾病合并肺性脑病的疗效观察  

Therapeutic effect observation of BiPAP respirator treating chronic obstructive pulmonary disease complicated with pulmonary encephalopathy

作　　者：危蕾[1] 刘芳英[1] 申燕华[1] 马伟[1] 王众福[1] 张善芳[1] 钱叶长[1] 

机构地区：[1]上海市宝山中心医院呼吸科,201900

出　　处：《国际呼吸杂志》2011年第19期1460-1462,共3页International Journal of Respiration

摘　　要：目的观察双水平气道正压通气（BiPAP）呼吸机治疗慢性阻塞性肺疾病（COPD）合并肺性脑病的疗效。方法将90例COPD合并肺性脑病患者分为两组。治疗组47例。对照组43例。对照组给予常规治疗，包括鼻导管吸氧，抗感染、祛痰止咳、解痉平喘、呼吸兴奋剂、平衡水电解质及纠正严重酸中毒等治疗，治疗组给予常规治疗及应用BiPAP呼吸机经面罩无创通气治疗。结果BiPAP呼吸机治疗后患者心率、呼吸频率、神志、PH、PaO2、PaCO2、SaO2均明显改善，各项指标及治疗成功率与对照组比较差异有统计学意义（P〈O．01）。结论BiPAP呼吸机治疗COPD合并肺性脑病具有肯定的疗效。Objective To investigate the clinic effect of the facemask bi-level positive airway pressure （BiPAP） assisted ventilation on patients of chronic obstructive pulmonary disease （COPD） with pulmonary encephalopathy. Methods The total of 90 patients of COPD with pulmonary encephalopathy were divided into two groups： treatment group （47 cases） and control group （43 cases）. The routine therapy was only given in the control group,but BiPAP assisted ventilation and the routine therapy both were given in the treatment group. The measures of heart rate （HR） ,of respiratory rate （RR）, sensorium and arterial gas analysis were observed before and after the treatment. Results The HR,RR,sensorium and arterial blood gas in the treatment group were significantly improved after ventilation. Compared with the control group, the foregoing parameters in the treatment group were superior. The difference was significant （ P 〈 0.01 ）. Conclusions BiPAP assisted ventilation is certainly effective to COPD with pulmonary encephalopathy.

关 键 词：慢性阻塞性肺疾病 肺性脑病 双水平气道正压通气呼吸机 

分 类 号：R563.9[医药卫生—呼吸系统]